Synthetic, an inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...
Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberber...
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostati...
Seco-Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Monomethylauristatin F Hcl(MMAF Hcl) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than...
Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic ...
M2 muscarinic receptor antagonist; myorelaxant. Steroid alkaloid derivative of Imperialine from the plant Petilium eduardi, and P. raddeanae.
Cobra Venom Factor
A non-toxic, complement-activating component of cobra venom Three polypeptide chains with molecular masses of about 70, 50, and 30 kDa, the two large subunits b...
a nicotinic cholinoreceptor antagonist at the neuromuscular junction; curare-like ganglioblocker. Bis-quaternary quinuclidine derivative, , synthetic.
Askendoside D presents a high selectivity for the cardiac Na+/K+-ATPase, with practically no activity on brain or kidney Na+/K+-ATPases, as compared with other ...
Sanguinarine is a toxic quaternary ammonium salt from the group of benzophenanthridine alkaloids. It is extracted from some plants, including bloodroot (Sanguin...
Aporphin alkaloid derivative of Isocorydine from plants of the Corydalis genus, Fumariaceae, a long-lasting ganglioblocker, with a sympathetic/parasympathetic a...
Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants includ...
Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Seco-Duocarmycin DMG is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
(Dap22)-ShK (ShK Dap22) peptide is a synthetic derivative of the well-known ShK toxin isolated from the venom of the Carribean sea anemone Stoichactis helianthu...
Fraxinellone is an insecticidal agent, inhibiting growth of larvae, used in the treatment and protection of crops and produce. Also, a naturally occurring compo...