Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumven...
Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibits microtubule assembly.
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Morphiceptin is a four amino acid peptide derived from the ß-casomorphin, a protein fragment itself derived from the digestion of milk protein casein. It is one...
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
DM 4 is an intermediate used to prepare semisynthetic maytansine analogs which can be conjugated with antibodies for the targeted treatment of cancer.
Nitrarine 2HCl is a hypotensive, spasmolytic, coronary dilator, sedative in experimental arrhythmias.
Synthetic, an inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX ...
Diterpenoid alkaloids from the roots of Delphinium scabriflorum.
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
Terpenoids found in the umbelliferae family act as agonists/antagonists for ER(alpha) and Erbeta.
Potent inhibitor of protein phosphatase tyoe 1 (PP1) and protein phosphatase tyoe 2A (PP2A).
A muscarinic receptors antagonist.
Complex of lanthanide element,an anticoagulant. The lanthanide element from Glutasam replaces calcium in its complex with prothrombine, thus preventing the form...
Steroidal Alkaloid from Convolvulus krauseanus
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Synthetic, a weak AChR antagonist.