Synthetic.alkaloid, a neuronal nicotinic AChR antagonist. Ganglioblocker.
A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and ...
Noscapine is often used as an antitussive medication.
A muscarinic receptors antagonist.
Amiloride HCl is a relatively selective inhibitor of the epithelial sodium channel, used in the management of hypertension and congestive heart failure.
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium c...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Synthetic, a neuronal nicotinic AChR antagonist.
Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
Apamin is an 18 amino acid peptide toxin found in bee venom. Apamin is used to elucidate the roles of these channels in cells and tissues expressing SK channels...
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Bicyclic diterpenoid of the clerodane series
Tropane alkaloid, from plants of the Convolvulus genus,
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.
Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple ...
Phencarol is used in the biological studies of azoniabicyclooctanes as muscarinic acetylcholine receptor antagonists.