An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
It was the main alkaloid found in medicinal plants Datura metel. .
A methyl easter of Okadaic acid. Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases.
Seco-Duocarmycin DMA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Calicheamicin is a potent DNA-binding cytotoxic antibiotic.Calicheamicin being the most notable enediyne antitumor antibiotics derived from the bacterium Microm...
Steroidal Alkaloid Derivative of Imperialine extracted from Petilium eduardi, a medium-lasting and selective M2 muscarinic receptors antagonist.
Diterpenoid , from plants of the Stevia genus, Compositae. Sweetener; reported as possessing anti-hypertensive effects upon hypertensive rats.
An anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
A muscarinic receptors antagonist.
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
alpha and beta Adrenoreceptors subtypes agonist; MAO inhibitor. Alkaloid derivative of l-Ephedrine from plants of the Ephedra genus, Ephedraceae.
Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
Etbicuphat is a GABAa receptor antagonist known to cause convulsions, seizures and other neuromuscular related episodes. Used in the study of anti-epileptic dru...
Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin ...
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contamina...
A hypolipidemic, antiatherosclerotic, anti-inflammatory agent, with angioprotective and hepatoprotective activity; antiulcerous. Sesquiterpene lactone , from pl...
Synthetic, a neuronal nicotinic AChR antagonist.
Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi. A potent medium-lasting selective M2 muscarinic receptor antagonist.