LDN-193189 - CAS 1062368-24-4
Not Intended for Therapeutic Use. For research use only.
Category:
Stem Cell Molecule
Product Name:
LDN-193189
Catalog Number:
1062368-24-4
CAS Number:
1062368-24-4
Description:
LDN193189 is a derivative of dorsomorphin that is a highly selective antagonist of BMP receptor isotypes ALK2 and ALK3 (IC50 of: 5 and 30 nM). The selectivity of LDN193189 for ALK2/3 is 200 fold over the TGF-B type receptors ALK4,-5 and -7. In murine smooth muscle cells, the compound inhibits BMP-4 induced phosphorylation of SMAD 1/5/8 with an IC50 of 5 nM.
Molecular Weight:
442.94
Molecular Formula:
C25H22N6 · HCl
COA:
Inquire
MSDS:
Inquire
Chemical Structure
CAS 1062368-24-4 LDN-193189