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Irofulven - CAS 158440-71-2

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Category
ADCs
Product Name
Irofulven
Synonyms
6-hydroxymethylacylfulvene; hydroxymethylacylfulvene; MGI 114; MGI-114.
CAS Number
158440-71-2
Description
Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and protein macromolecules, forms adducts, and arrests cells in the S-phase of the cell cycle. This a
Molecular Weight
246.12
Molecular Formula
C15H18O3
COA
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MSDS
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Canonical SMILES
CC1=C(C2=C(C3(CC3)[C@@](C(=O)C2=C1)(C)O)C)CO
InChI
InChI=1S/C15H18O3/c1-8-6-10-12(11(8)7-16)9(2)15(4-5-15)14(3,18)13(10)17/h6,16,18H,4-5,7H2,1-3H3/t14-/m0/s1
InChIKey
NICJCIQSJJKZAH-AWEZNQCLSA-N
Tag
ADCs Cytotoxin
Structure
CAS 158440-71-2 Irofulven
Specification
Purity
≥95%
Appearance
Soild powder
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