BOC Sciences always keeps an eye on the latest findings and advancements in the field to ensure its chemicals and services are served in the most easily applied state and the fastest accessed mode, which especially facilitates research and production activities that are time sensitive. This section is a spotlight of the latest news in pharmaceutical and general chemistry areas, also serving as references for visitors. Typically, most of the mentioned chemicals and technologies can be found at BOC Sciences, and the advances in technologies are or will be applied by BOC Sciences for better results.
Recently, machine learning (ML) has made major progress in the field of chemistry, especially for the search engine ranging from drug screening, batteries design to OLEDs design and catalysts discovery. Against this backdrop, an idea came to the minds of scientists from Google: maybe the widely discussed artificial intelligence (AI) can be also used in ML. The super-human ability of AI in pathological diagnosis has already been found. A good example is AI can effortlessly complete the work of breast cancer diagnosis, which will consume 30 hours of professionals and the results are even less accurate.
Recently, at the annual meeting of the American Society of Clinical Oncology at the United States in 2017, researchers from multinational reported and exchanged their latest study results, the most noteworthy of which was the development of new drugs for the treatment of multiple types of cancers. Here, we sort out about this.
Xadago (safinamide) as an add-on treatment for levodopa/carbidopa cooperatively developed by two Italian companies-Zambon Pharma and Newron Pharmaceutical against Parkinson’s disease was approved by FDA for marketing in March. Of mention, Xadago is the first new drug got FDA approval over the recent decade for the disease, which is the second most common neurodegenerative disease among the elders. It’s estimated that about one to two in every one hundred people over 65 are in the condition. And the number is increasing with the trend of global aging, whilst few drugs are found effective to control the disease. The data released by the National Institutes of Health showed that about 50,000 people are newly diagnosed with the Parkinson’s disease annually.
A natural product is a chemical compound or substance produced by a living organism-found in nature that usually has a pharmacological or biological activity for use in pharmaceutical drug discovery and drug design. This product can be considered as such even if it can be prepared by total synthesis. And it is usually secondary metabolite. Secondary metabolite has functions that are not directly involved in the growth, development or reproduction of the organism. It is generally produced as a defense mechanism against predators or to aid the organism adapting to its surrounding environment. Natural products could be extracted from tissues of terrestrial plants, marine organisms or microorganism fermentation broths. A crude (untreated) extract from any one of these sources typically contains novel, structurally diverse chemical compounds.