IDE-2 - CAS 1136466-93-7
Not Intended for Therapeutic Use. For research use only.
Category:
Stem Cell Molecule
Product Name:
IDE-2
Catalog Number:
1136466-93-7
CAS Number:
1136466-93-7
Description:
IDE-2 was identified in a high throughput screen as an inducer of definitive endoderm (IDE) from embryonic stem (ES) cells. IDE-2 is able to generate Sox17+/FoxA2+ cells to an equal or greater efficiency than that of protein (i.e. Activin A or Nodal) IDEs in mouse or human ES cell cultures. It functions in part via activation of TGF-β signaling, as evident by Smad2 phosphorylation. IDE-2 chemically induced endoderm can continue to differentiate into pancreatic progenitors in vitro and contribute to gut tube formation in vivo when injected into the developing gut tube of mouse embryos.
Molecular Weight:
240.3
Molecular Formula:
C12H20N2O3
COA:
Inquire
MSDS:
Inquire
Chemical Structure
CAS 1136466-93-7 IDE-2