Extract from roots of Aconitum piepunense. A new chemical class of ganglioblocker, myorelaxant of reversible type.
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
A muscarinic receptors antagonist.
a nicotinic cholinoreceptor antagonist at the neuromuscular junction; curare-like ganglioblocker. Bis-quaternary quinuclidine derivative, , synthetic.
Batrachotoxin (BTX) is an extremely potent cardiotoxic and neurotoxic steroidal alkaloid found in certain species of frogs, melyrid beetles, and birds.Batrachot...
TTX is a potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through voltage-activated sodium (NaV) channels, blocking nerve and...
Delsoline is a hypotensive alkaloid isolated from Aconitum.
A proanthocyanidin from Polygonum coriaricum, an antihypoxic.
Seco-Duocarmycin DMA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
Steroidal Alkaloid from Convolvulus krauseanus
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily , surprise lilies, and daffodils. It may be h...
Calicheamicin is a potent DNA-binding cytotoxic antibiotic.Calicheamicin being the most notable enediyne antitumor antibiotics derived from the bacterium Microm...
Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker.
Melamine is a widely used, broad-spectrum benzimidazole fungicide and a metabolite of benomyl. It is also employed as a casting worm control agent in amenity tu...
Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
Muscarinic toxin 2
Muscarinic toxin 2 (MT2) is one member of a family of small peptides of 65 amino acid residues of around 7076 daltons in molecular weight derived from the venom...
a CNS stimulant. Alkaloid, , purified from plants of Coffea genus, Rubiaceae.