|Description||Selective blocker of the big conductance Ca2+-activated K+ channel.|
Condelphine was isolated from the roots of Delphinium denudatum. A nicotinic receptor antagonist at the neuromuscular junction and ganglioblocking agent.
Potent inhibitor of protein phosphatase tyoe 1 (PP1) and protein phosphatase tyoe 2A (PP2A).
Synthetic.alkaloid, a neuronal nicotinic AChR antagonist. Ganglioblocker.
Trichodesmine is a pyrrolizidine alkaloid that has neurotoxic effects and is naturally found in Crotolaria argyptiaca, a shrub plant that is native to the south...
Monomethylauristatin F Hcl(MMAF Hcl) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than...
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
Protopine is a benzylisoquinoline alkaloid occurring in opium poppy, Corydalis tubers and other plants of the family papaveraceae, like Fumaria officinalis. It ...
A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and ...
Rebaudioside A is a glycoside from the stevia plant. Rebaudioside A is used as a sweetener with sweetness about 300 times that of sugar with negligible effect o...
Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 acti...
Bicyclic diterpenoid of the clerodane series
Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and pr...
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Doxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
Triterpene glycoside Extracted from Dipsacus azureas
A microtubule-disrupting agent.
Notexin exerts both presynaptic (blocks the release of acetylcholine) and myotoxic<br/>activities
An excitatory scorpion toxin. Polypeptide, of 77 amino acids cross-linked by 4 disulfide bridges. Recombinant toxin produced in<br/>Escherichia coli initialy fr...
Unsevine acts directly on the CNS, inhibits the reaction of orientation, prolongs the action of soporifics, enhances the effects of analgesics and prevents conv...
Synthetic, a weak AChR antagonist.