(±)-Huperzine A - CAS 120786-18-7
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
(±)-Huperzine A
Catalog Number:
120786-18-7
Synonyms:
Huperzine A
CAS Number:
120786-18-7
Description:
Huperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-κB nuclear localization and activation. Huperzine A is a potential therapeutic agent for Alzheimer's disease.
Molecular Weight:
242.32
Molecular Formula:
C15H18N2O
COA:
Inquire
MSDS:
Inquire
Targets:
AChE
Chemical Structure
CAS 120786-18-7 (±)-Huperzine A

Related AChE Products


CAS 1953-04-4 Galanthamine HBr

Galanthamine HBr
(CAS: 1953-04-4)

Galanthamine is an AChE inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase.

Ganstigmine hydrochloride
(CAS: 412044-92-9)

Ganstigmine hydrochloride is a selective inhibitor of AChE as a useful therapeutic drug for Alzheimer's disease patients with cognitive impairment accompanied b...

CAS 125-51-9 Pipenzolate bromide

Pipenzolate bromide
(CAS: 125-51-9)

Pipenzolate bromide, a muscarinic receptor antagonist, was once considered as a spasmolytic.

CAS 59-99-4 Neostigmine

Neostigmine
(CAS: 59-99-4)

Neostigmine is a parasympathomimetic compound, which acts as a reversible acetylcholinesterase inhibitor. It is used in the treatment of myasthenia gravis, ogil...

Icopezil maleate
(CAS: 145815-98-1)

The maleate salt form of Icopezil, a benzoxazol derivative, has been found to be an acetylcholinesterase inhibitor and was once studied for the treatment of Alz...

CAS 52-68-6 Trichlorfon

Trichlorfon
(CAS: 52-68-6)

Trichlorfon is an irreversible organophosophate acetylcholinesterase inhibitor used as an insecticide for the control of flies and roaches.

CAS 102518-79-6 (-)-Huperzine A (HupA)

(-)-Huperzine A (HupA)
(CAS: 102518-79-6)

(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G...

CAS 510-77-0 Galanthaminone

Galanthaminone
(CAS: 510-77-0)

Galantamine is a competitive and reversible cholinesterase(AChE) inhibitor, which is used for the treatment of mild to moderate Alzheimer's disease and various ...

CAS 209349-27-4 Ladostigil

Ladostigil
(CAS: 209349-27-4)

Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer’s disease. Ladostigil is...

CAS 51-15-0 Pralidoxime chloride

Pralidoxime chloride
(CAS: 51-15-0)

Pralidoxime is an antidote to organophosphate pesticides, reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organoph...

CAS 209394-46-7 Ladostigil tartrate

Ladostigil tartrate
(CAS: 209394-46-7)

Ladostigil, also called as TV-3,326, is a novel neuroprotective agent developed to treat neurodegenerative disorders sunch as Alzheimer’s disease. Ladostigil is...

CAS 129101-54-8 Rivastigmine Tartrate

Rivastigmine Tartrate
(CAS: 129101-54-8)

Rivastigmine Tartrate is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to mod...

CAS 123441-03-2 Rivastigmine

Rivastigmine
(CAS: 123441-03-2)

Rivastigmine, a carbamate derivative, is a reversible cholinesterase inhibitor that is selective for the central nervous system to treat Alzheimer's Disease.

CAS 116-38-1 Edrophonium chloride

Edrophonium chloride
(CAS: 116-38-1)

Edrophonium chloride is a reversible Acetylcholinesterase inhibitor which is effective in avoiding the decomposition of the neurotransmitter acetylcholine compe...

CAS 1225-55-4 Protriptyline hydrochloride

Protriptyline hydrochloride
(CAS: 1225-55-4)

The hydrochloride salt of Protriptyline which is a norepinephrine uptake blocker that could be effective as an antidepressant.

AP2238
(CAS: 553681-56-4)

AP2238 is a inhibitor of both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.

CAS 121-54-0 Benzethonium Chloride

Benzethonium Chloride
(CAS: 121-54-0)

Benzethonium chloride is a potent inhibitor of nAChRs, it inhibits α4β2 nAChRs and α7 nAChRs with IC50 of 49 nM and 122 nM, respectively.

Neostigmine Iodide
(CAS: 1212-37-9)

This active molecular is a reversible acetylcholinesterase inhibitor as a parasympathomimetic compound under the development of Flamel Technologies. Neostigmine...

CAS 122892-31-3 Itopride hydrochloride

Itopride hydrochloride
(CAS: 122892-31-3)

Reversible AChE inhibitor. D2 receptor antagonist. Raises motilin and somatostatin levels. Lowers CCK levels. Shows gastroprokinetic effects in vivo. Orally act...

CAS 314-03-4 Pimethixene

Pimethixene
(CAS: 314-03-4)

Pimethixene, also called as BP 400 or Calmixène, with antihistamine and anticholinergic properties it treats hyperactivity, anxiety, sleep disorders, and allerg...