GSK429286A - CAS 864082-47-3
Not Intended for Therapeutic Use. For research use only.
Category:
Stem Cell Molecule
Product Name:
GSK429286A
Catalog Number:
864082-47-3
CAS Number:
864082-47-3
Description:
GSK429286A is a cell-permeable, selective small molecule inhibitor of Rho-associated, coiled-coil containing protein kinase (ROCK). ROCKs are serine/threonine specific protein kinases which play a crucial role in organization of the actin cytoskeleton. ROCK inhibitors have been found to prevent apoptosis, as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their self-renewal properties or pluripotency. Due to GSK429286A’s specificity, this reagent may be useful in assessing the cellular roles of individual ROCK isoforms.
Molecular Weight:
432.38
Molecular Formula:
C21H16F4N4O2
COA:
Inquire
MSDS:
Inquire
Chemical Structure
CAS 864082-47-3 GSK429286A