PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX ...
Gossypol Acetic Acid
an antiviral at low concentration; antiherpes, antipsoriasis and antikeratitis, male contraceptive. Polyphenol , from plants of the Gossypium genus, Malvaceae.
A muscarinic receptors antagonist.
Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Xanthonoid Purified from Hypericum perforatum
Scyllatoxin (Leiurotoxin-1) is a neurotoxin that was originally isolated from Leiurus quinquestriatus hebraeus. Scyllatoxin binds and blocks SK channels (small ...
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
Synthetic organophosphorous compound, a non-competitive GABA antagonist; potent convulsant: causes epileptoform seizures.
Ca2+-Activated K+ Channel Blocker
Quinoline Alkaloid Extracted from Haplophyllum bucharicum
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Dihydropyridine calcium channel blocker. Antianginal; antihypertensive.
An anthelmintic: blocks the enzymatic process responsible for the absorption of glucose by parasites, causing their death. Benzimidazole derivative , synthetic.
Ricinine is an alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). Ricinine is a central nervous system stimulant that could potential...
Lignan , from plants of the Rutaceae family, a substance presenting an estrogenic activity and sedative effects. .
Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1....
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Diterpenoid , from plants of the Stevia genus, Compositae. Sweetener; reported as possessing anti-hypertensive effects upon hypertensive rats.
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.