Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, identifies an inflammatory subpopulation of macrophages in...
Amaryllidaceae alkaloid from plants of the Amaryllidaceae family. A hypotensive, sedative. Amaryllidaceae alkaloid , from plants of the Amaryllidaceae family.
Extract from roots of Aconitum piepunense. A new chemical class of ganglioblocker, myorelaxant of reversible type.
Seco-Duocarmycin DME is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Alkaloid, extracted from Thalictrum isopyroide.
Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
α-Cobratoxin is a substance of the venom of certain Naja cobras. It is a nicotinic acetylcholine receptor (nAChR) antagonist which causes paralysis by preventin...
β-Pompilidotoxin slows the inactivation of neuronal Navs. β-Pompilidotoxin was isolated from the venoms of two wasps, Anoplius amariensis and Batozonellus macul...
A nicotinic antagonist.
Aconitine (AC), an active/toxic alkaloid from Aconitum species, is commonly present in Traditional Chinese Medicine (TCM) prescriptions because of the great eff...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Phencarol is used in the biological studies of azoniabicyclooctanes as muscarinic acetylcholine receptor antagonists.
Calicheamicin is a potent DNA-binding cytotoxic antibiotic.Calicheamicin being the most notable enediyne antitumor antibiotics derived from the bacterium Microm...
Noscapine is often used as an antitussive medication.
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activ...
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 acti...
[Tyr2]-Scyllatoxin allows labelling by iodination. 31-amino acid polypeptide with 3 disulfide bridges. , synthetic, originally from Leiurus quinquestriatus hebr...
Methimazole inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone synthesis by oxidizing the anion iodide (I−) to iodine (I2), hypoiodous ...