(-)-GLOBULOL - CAS 489-41-8
Category:
Main Product
Product Name:
(-)-GLOBULOL
Catalog Number:
489-41-8
Synonyms:
(-)-GLOBULOL; GLOBULOL, (-)-; [1aR-(1aalpha,4alpha,4aalpha,7alpha,7abeta,7balpha)]-decahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulen-4-ol; (-)-GLOBULOL PURISS 98.5%; (1aR,4aβ,7aα,7bβ)-Decahydro-1,1,4,7β-tetramethyl-1H-cycloprop[e]azulen-4β-ol; (1R,3aα,8aβ)-
CAS Number:
489-41-8
Molecular Weight:
222.37
Molecular Formula:
C15H26O
Quantity:
Data not available, please inquire.
COA:
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MSDS:
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Chemical Structure
CAS 489-41-8 (-)-GLOBULOL

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Reference Reading


1.Chemical constituents of essential oils from the leaves, stems, roots and fruits of Alpinia polyantha.
Huong le T, Thang TD, Ogunwande IA. Nat Prod Commun. 2015 Feb;10(2):367-8.
The essential oils obtained from the leaves, stems, roots and fruits of Alpinia polyantha D. Fang (Zingiberaceae) have been studied. The leaf oil was comprised mainly of camphor (16.1%), α-pinene (15.2%) and β-agarofuran (12.9%), while the major constituents of the stem oil were α-pinene (12.4%), β-cubebene (10.6%), β-agarofuran (10.3%) and globulol (8.8%). However, β-cubebene (12.6%), fenchyl acetate (10.8%), β-maaliene (9.0%), aristolone (8.8%) and α-pinene (8.2%) were the compounds occurring in higher amounts in the root oil. The quantitatively significant compounds of the fruit oil were δ-cadinene (10.9%), β-caryophyllene (9.1%), β-pinene (8.7%) and α-muurolene (7.7%).
2.Chemical composition of volatile and fixed oils from of Salvia argentea L. (Lamiaceae) growing wild in Sicily.
Riccobono L1, Maggio A1, Rosselli S1, Ilardi V2, Senatore F3, Bruno M1. Nat Prod Res. 2016;30(1):25-34. doi: 10.1080/14786419.2015.1030742. Epub 2015 Apr 16.
The chemical compositions of the essential oil and of the non-polar extracts (petroleum ether, dichloromethane) of the aerial parts (flowers, leaves and stems) of Salvia argentea L. were determined by GC-FID and gas chromatography-mass spectrometry analysis. 14-Hydroxy-α-humulene (40.1%) was recognised as the main constituents of the essential oil of S. argentea, together with 1,3,8-p-menthatriene (12.1%), globulol (7.4%) and β-sesquiphellandrene (5.8%). Tritriacontane (9.9% and 14.1%), heptacosane (8.4% and 10.5%), hentriacontane (8.3% and 10.9%), tetradecanal (8.4% and 10.2%) and methyldotriacontane (7.9% and 7.6%) were recognised as the main constituents of the extracts in petroleum ether and dichloromethane, respectively, whereas methyl linolenate (36.6% and 13.5%) and methyl myristoleate (10.5% and 18.5%) were recognised as the main constituents of the methylated extracts.
3.The monoamine oxidase inhibitory activity of essential oils obtained from Eryngium species and their chemical composition.
Klein-Júnior LC1, Dos Santos Passos C1, Tasso de Souza TJ1, Gobbi de Bitencourt F1, Salton J1, de Loreto Bordignon SA2, Henriques AT1. Pharm Biol. 2016 Jun;54(6):1071-6. doi: 10.3109/13880209.2015.1102949. Epub 2016 Jan 25.
Context Monoamine oxidase (MAO) inhibitors are used in the treatment of depression, anxiety disorders, and the symptomatic treatment of Parkinson's disease. Eryngium, the most representative of the Apiaceae family, is well known for the presence of essential oils (EOs), which have already demonstrated MAO inhibitory potential. Objective The objective of this study is to evaluate the MAO inhibitory capacity of the EOs obtained from Eryngium floribundum Cham. & Schlecht. (EF), E. eriophorum Cham. & Schlecht. (EE), E. nudicaule Lam. (EN), E. horridum Malme (EH), and E. pandanifolium Cham. & Schlecht. (EP). Materials and methods EOs were obtained from fresh whole plants by hydrodistillation (3 h). Chemical analyses were performed by GC/MS using apolar and polar columns, with oven temperature from 60 to 300 °C at 3 °C/min. The MAO-A and -B activities were evaluated in vitro by an end-point method using kynuramine as the substrate and mitochondrial suspension or human recombinant enzymes as the enzymatic source.
4.Phytotoxic activity and chemical composition of aqueous volatile fractions from Eucalyptus species.
Zhang J1, An M2, Wu H3, Liu de L3, Stanton R3. PLoS One. 2014 Mar 28;9(3):e93189. doi: 10.1371/journal.pone.0093189. eCollection 2014.
The essential oils from four Eucalyptus species (E. spathulata, E. salubris, E. brockwayii and E. dundasii) have been previously confirmed to have stronger inhibitory effects on germination and seedling growth of silverleaf nightshade (Solanum elaeagnifolium Cav.). The aqueous volatile fractions (AVFs) were the water soluble volatile fractions produced together with the essential oils (water insoluble fractions) during the steam distillation process. The aim of this study was to further assess the phytotoxicity of AVFs from the four Eucalyptus species and their chemical composition. The fresh leaves of the four Eucalyptus species were used for the extraction of AVFs. The AVFs were tested for their phytotoxic effects on the perennial weed, silverleaf nightshade under laboratory conditions. The chemical compositions of the AVFs were determined by gas chromatograph-mass spectrometry (GC-MS). Our results showed that the AVFs had strong inhibition on the germination and seedling growth of silverleaf nightshade.