GERANIOL BRI FCC - CAS 106-24-1
Category:
Flavor & Fragrance
Product Name:
GERANIOL BRI FCC
Synonyms:
2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-, GERANIOL BRI FCC, Meranol
CAS Number:
106-24-1
Molecular Weight:
154.26
Molecular Formula:
C10H18O
COA:
Inquire
MSDS:
Inquire
Olfactive Family:
Others
FEMA:
2507
Odor description:
A very high quality rose/lemon odor.
Chemical Structure
CAS 106-24-1 GERANIOL BRI FCC

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Reference Reading


1.Engineering Escherichia coli for high-yield geraniol production with biotransformation of geranyl acetate to geraniol under fed-batch culture.
Liu W1, Xu X2, Zhang R2, Cheng T3, Cao Y3, Li X3, Guo J4, Liu H3, Xian M3. Biotechnol Biofuels. 2016 Mar 11;9:58. doi: 10.1186/s13068-016-0466-5. eCollection 2016.
BACKGROUND: Geraniol is an acyclic monoterpene alcohol, which exhibits good prospect as a gasoline alternative. Geraniol is naturally encountered in plants at low concentrations and an attractive target for microbial engineering. Geraniol has been heterologously produced in Escherichia coli, but the low titer hinders its industrial applications. Moreover, bioconversion of geraniol by E. coli remains largely unknown.
2.X-ray structure of linalool dehydratase/isomerase from Castellaniella defragrans reveals enzymatic alkene synthesis.
Weidenweber S1, Marmulla R2, Ermler U1, Harder J2. FEBS Lett. 2016 Apr 7. doi: 10.1002/1873-3468.12165. [Epub ahead of print]
Linalool dehydratase/isomerase (Ldi), an enzyme of terpene degradation in Castellaniella defragrans, isomerizes the primary monoterpene alcohol geraniol into the tertiary alcohol (S)-linalool and dehydrates (S)-linalool to the alkene β-myrcene. Here we report on the crystal structures of Ldi with and without terpene substrates, revealing a cofactor-free homopentameric enzyme. The substrates were embedded inside a hydrophobic channel between two monomers of the (α,α)6 barrel fold class and flanked by three clusters of polar residues involved in acid-base catalysis. The detailed view into the active site will guide future biotechnological applications of Ldi, in particular, for industrial butadiene and isoprene production from renewable sources. This article is protected by copyright. All rights reserved.
3.Preventive Effect of Geraniol on Diethylnitrosamine-Induced Hepatocarcinogenesis in Rats.
Sawada S1, Okano J1, Imamoto R1, Yasunaka Y1, Abe R1, Koda M1, Murawaki Y1, Isomoto H1. Yonago Acta Med. 2016 Mar;59(1):37-43. Epub 2016 Apr 1.
BACKGROUND: Geraniol is a plant-derived phytochemical possessing anti-cancer action. The anti-carcinogenic effect of geraniol was investigated in the diethylnitrosamine (DEN)-induced hepatocarcinogenic rat model.
4.Linalool isomerase, a membrane-anchored enzyme in the anaerobic monoterpene degradation in Thauera linaloolentis 47Lol.
Marmulla R1, Šafarić B1, Markert S2, Schweder T2, Harder J3. BMC Biochem. 2016 Mar 15;17(1):6. doi: 10.1186/s12858-016-0062-0.
BACKGROUND: Thauera linaloolentis 47Lol uses the tertiary monoterpene alcohol (R,S)-linalool as sole carbon and energy source under denitrifying conditions. The conversion of linalool to geraniol had been observed in carbon-excess cultures, suggesting the presence of a 3,1-hydroxyl-Δ(1)-Δ(2)-mutase (linalool isomerase) as responsible enzyme. To date, only a single enzyme catalyzing such a reaction is described: the linalool dehydratase/isomerase (Ldi) from Castellaniella defragrans 65Phen acting only on (S)-linalool.