|Description||Quinoline alkaloid , from plants of the Rutaceae family, an anticonvulsant; causes hypothermia; inhibits the reaction of orientation; prevents cardiac arrhythmia caused by electric stimulation of the auricule or by Aconitine.|
DC-1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Known as a weak hypotensive, moderate M- and N-cholinolytic pyrrolizidine alkaloid, xtracted from Trachelanthus Korolkowia.
Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 acti...
Potent inhibitor of protein phosphatase tyoe 1 (PP1) and protein phosphatase tyoe 2A (PP2A).
Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...
Synthetic, from Scorpio maurus palmatus scorpion venom. An activator of Ca2+ release channel/ryanodine receptors. 33-mer basic peptide cross-linked by three dis...
Anhydroperforine from the seeds of Haplophyllum perforatum.
Tschimgine a substance presenting an estrogenic activity..
PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compa...
Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
anti-hypoxic; acts on the mitochondrial respiratory chain; prevents atherosclerosis; angioprotector. Sum of polymerized Proantocyanides , from the plants of Fab...
Hydrochloride salt of DL-Tetrahydropalmatine is the main active substance of the Chinese herb corydalis which induces hypotension and bradycardia in rats throug...
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activ...
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria.
Harmaline is a fluorescent psychoactive indole alkaloid from the group of harmala alkaloids and beta-carbolines. It is the partially hydrogenated form of harmin...
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostati...
Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic ...
Diterpenoid alkaloids from the roots of Delphinium scabriflorum.
C20-diterpenoid alkaloid , from the Ranunculaceae family,an antiarrhythmic.