Seco-Duocarmycin MA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Synthetic, GABAA-gated Cl- channels blocker; non-competitive GABAA antagonist.
Nudicauline is extracted from plants of the Ranunculaceae family, a Alpha-Bungarotoxin neuronal nicotinic receptor.
An anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
alpha and beta Adrenoreceptors subtypes agonist; MAO inhibitor. Alkaloid derivative of (+)-Pseudoephedrine from plants of the Ephedra genus, Ephedraceae.
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab ma...
Extractedfrom Vinca erecta. A dopamine receptor stimulating agent Indolinine alkaloid
Deltaline has a lycoctonine carbon-atom skeleton with four six-membered rings and three five-membered rings among; three of the six-membered rings adopt chair c...
Non-selective K+ channel blocker.
Synthetic, an inhibitor of monoamine oxydase.
Synthetic.alkaloid, a neuronal nicotinic AChR antagonist. Ganglioblocker.
DM 4 is an intermediate used to prepare semisynthetic maytansine analogs which can be conjugated with antibodies for the targeted treatment of cancer.
Extrat from the seeds of Corchorus olitoriu, a cardiac Glycoside.
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostati...
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activ...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Indole alkaloid Amaryllidaceae Fam. Plants
Complex of lanthanide element,an anticoagulant. The lanthanide element from Glutasam replaces calcium in its complex with prothrombine, thus preventing the form...
A SR-4 agonist with moderate activity as a SR-3 antagonist