Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Dendrotoxin-I is a highly selective blocker of voltage-gated K+<br/>channels (KV1.1 and KV1.2), as well as heteromultimeric channels containing these, with othe...
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX ...
Fraxinellone is an insecticidal agent, inhibiting growth of larvae, used in the treatment and protection of crops and produce. Also, a naturally occurring compo...
Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function. It intercalates into DNA and, when activated by ultraviol...
C19-norditerpenoid alkaloid , from plants of the Ranunculaceae family, a potent antiarrhythmic, antifibrillatory; Na+ channel blocker in cardiomyocytes.
α-conotoxin MI (alpha-conotoxin MI) is a conotoxin that has been isolated from the venom of the cone snail Conus magus. α-conotoxin MI is a competitive antagoni...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Unsevine acts directly on the CNS, inhibits the reaction of orientation, prolongs the action of soporifics, enhances the effects of analgesics and prevents conv...
Kaliotoxin (1-37)NH2 is a selective voltage-dependent K+ channels blocker, a blocker of Ca2+-activated K+ channels of high conductance and some voltage-dependen...
Talatisamine inhibits the enhanced I(K) caused by Aβ40 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss ...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
a CNS stimulant. Alkaloid, , purified from plants of Coffea genus, Rubiaceae.
Seco-Duocarmycin DMG is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Diterpenoid alkaloids from the roots of Delphinium scabriflorum.
An anthelmintic: blocks the enzymatic process responsible for the absorption of glucose by parasites, causing their death. Benzimidazole derivative , synthetic.
ω-agatoxin-IVA (ω-AGA IVA) is a peptide originally isolated from funnel web-spider venom Agelenopsis aperta. This peptide is a specific blocker of P/Q-type calc...
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
A potent non-competitive GABA antagonist in mammalian, molluscan and insects; convulsant;laboratory insecticide.