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Eudesmine - CAS 526-06-7

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Category
ADCs
Product Name
Eudesmine
Catalog Number
526-06-7
CAS Number
526-06-7
Description
Lignan , from plants of the Rutaceae family, a substance presenting an estrogenic activity and sedative effects. .
Molecular Weight
386.44
Molecular Formula
C22H26O6
COA
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MSDS
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Tag
ADCs Cytotoxin
Structure
CAS 526-06-7 Eudesmine
Specification
Purity
97 % (TLC).
Melting Point
107-108 °C.
Appearance
Solid powder
Application
ADCs Cytotoxin
Storage
Store at +4 °C, in dark place.
Solubility
chloroform; very slightly in alcohol and acetone; not in water.
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Reference Reading
1.[Eudesmane sesquiterpenes from twigs of Manglietia hookeri].
Qi MG, Zhang F, Wang WS, Wu HB, Yuan HC, Jiao YG, Dong XJ. Zhongguo Zhong Yao Za Zhi. 2015 Aug;40(16):3229-32.
Chemical constituents from the acetone extract of twigs of Manglietia hookeri were isolated and purified by various column chromatographic methods over silica gel and sephadex LH-20, and preparative TLC. The structures of these compounds were identified on the basis of physicochemical properties and spectral analysis, including NMR and MS spectra. Six eudesmane sesquiterpenes were obtained and their structures were identified as trans-eudesmane-4, 11-diol(1), β-eudesmol(2), (-) -10-epi-5β-hydroxy-β-eudesmol (3), epi-carrisone (4), 6-hydroxy-eudesm-4(14) -ene(5) and gynurenol(6). All the compounds were isolated from this plant for the first time. Furthermore, the 13C-NMR data of compound 3 were reported for the first time.
2.New eudesmane-type sesquiterpenoids from the root bark of Pseudolarix kaempferi.
Jiang HL1,2, Ha W1, Shi YP1. J Asian Nat Prod Res. 2015 Dec;17(12):1180-7. doi: 10.1080/10286020.2015.1117455. Epub 2015 Dec 14.
The phytochemical investigation of the root bark of Pseudolarix kaempferi yielded eight eudesmane-type sesquiterpenoids, including three new ones, 1α-hydroxyl-4(14)-en-β-dihydroagarafuran (1), 1α, 2α-diacetoxy-8β-isobutanoyloxy-9α-benzoyl oxy-15-β-(β-furancarbonyloxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (7), and 1α-acetoxy-2 α-furancarbonyloxy-8β-isobutanoyloxy-9α-benzoyloxy-15β-(β-acetoxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (8). Herein the new compounds 7 and 8 were reported as a mixture. The molecular structures of the isolated compounds were elucidated on the basis of extensive spectroscopic analysis, including UV, IR, NMR, and MS, and comparison with the literature data.
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