|Description||GABA receptor antagonist|
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Hydrochloride salt of DL-Tetrahydropalmatine is the main active substance of the Chinese herb corydalis which induces hypotension and bradycardia in rats throug...
Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...
A terpenoid complex ester , from plants of the Umbelliferae family, a substance presenting an estrogenic activity.
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
Extract from plants of the Leguminosae family, an antiatherosclerotic and angioprotective, reduces platelet aggregation.
Potent, reversible acetylcholinesterase inhibitor
Daunorubicin(RP13057) inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.
Diterpenoid Alkaloid Extracted from Aconitum orientale
Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostati...
Aconitine (AC), an active/toxic alkaloid from Aconitum species, is commonly present in Traditional Chinese Medicine (TCM) prescriptions because of the great eff...
Scyllatoxin (Leiurotoxin-1) is a neurotoxin that was originally isolated from Leiurus quinquestriatus hebraeus. Scyllatoxin binds and blocks SK channels (small ...
Seco-Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Carothane complex ester , from plants of the Umbelliferae family.
Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ relea...
Melittin inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane) and is a ce...
Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity agai...
A spasmolytic agent, shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.