|Synonyms||EGC; Epigallocatechin; l-Epigallocatechin; epi-Gallocatechin|
|Description||(-)-Epigallocatechin is the most abundant flavonoid in green tea. It is a major green tea polyphenol with antioxidant, anti-inflammatory, and anticancer activities. It can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. It is a potent inhibitor of amyloidogenic cystatin I66Q amyloid fibril formation in vitro. It prevents amyloidogenic cystatin fibril formation by stabilizing the molecule in its native-like state as opposed to redirecting aggregation to disordered, amorphous aggregates. It induced the formation of hydroxyl radicals in E. faecalis. It has been shown to scavenge DPPH radicals and prevent the growth of several different AML cell lines at micromolar concentrations.|
Formononetin is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone.
MK 0927 is a potential bio-active agent., but no detail information has been published yet.
Clofibric acid is a PPAR agonist.
Evofosfamide, also known as TH-302, is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic act...
HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. As expect...
CK 683A is a bio-active chemical，but no detailed information has been published yet.
GYKI-20238 is a thiazolidine compound with anti-amnesic activity.
CGP 47072, a bisphosphonate derivative, has been found to be a calcium regulator and was once studied in the treatment of osteoporosis.
Sevelamer is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease. It consists of polyallylamine that is crosslinked...
Norelgestromin is a metabolite of Norgestimate which is a steroidal progestin.
2'-Deoxyguanosine HCl is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
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Probenecid inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. It is able to prevent the efflux of calcium-sensitive fluor...
Faropenem potassium is an orally active beta-lactam antibiotic. It is a prodrug of Faropenem and belongs to the penem group. It is resistant to some forms of ex...
Calcium D-Panthotenate, also called vitamin B5 Calcium, is a water-soluble vitamin and an essential nutrient for many animals.
Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)
BMS-419437 is a synthetic organic bio-active chemical.
Furaltadone HCl is an antibacterial and has distinct curative effect in the treatment of coccidiosis.
GSK-1440115 is an orally active urotensin II receptor antagonist. It is used for the treatment of asthma.
Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any ...