|Synonyms||EGC; Epigallocatechin; l-Epigallocatechin; epi-Gallocatechin|
|Description||(-)-Epigallocatechin is the most abundant flavonoid in green tea. It is a major green tea polyphenol with antioxidant, anti-inflammatory, and anticancer activities. It can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. It is a potent inhibitor of amyloidogenic cystatin I66Q amyloid fibril formation in vitro. It prevents amyloidogenic cystatin fibril formation by stabilizing the molecule in its native-like state as opposed to redirecting aggregation to disordered, amorphous aggregates. It induced the formation of hydroxyl radicals in E. faecalis. It has been shown to scavenge DPPH radicals and prevent the growth of several different AML cell lines at micromolar concentrations.|
Choline Fenofibrate is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipide...
20-O-Acetylingenol-3-angelate is a natural compound extracted from Euphorbia conspicua N. E. Br. It is used as molluscicidal agent, anti-cancer agent and cytost...
A 438079 hydrochloride
A 438079 hydrochloride is a competitive P2X7 receptor antagonist with pIC50 value of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell li...
CC-17369, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma.
Guanoxyfen sulfate is an inhibitor of vasoconstrictor responses to sympathetic nerve stimulation. It could potentiate the actions of adrenaline and noradrenalin...
Amifostine is a phosphorylated aminosulfhydryl compound. After dephosphorylation of amifostine by alkaline phosphatase to an active free sulfhydryl (thiol) meta...
Cgp 43902A is a bio-active molecular, but no detailed information has been published yet.
Fenofibric acid is a lipid regulating agent available as delayed release capsules for oral administration.
CP-69799 is an inhibitor of aspartate proteinases.
CP-394531 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in a...
CCT007093 is a potent PPM1D inhibitor or WIP1 inhibitor that selectively reduces viability of human tumour cell lines
LY 135305 is a bio-active molecular under the development of Eli Lilly. It can inhibit spontaneous lung metastasis in a dose-dependent manner.
Pamidronate disodium pentahydrate
Pamidronate disodium pentahydrate is a nitrogen-containing bisphosphonate, used to prevent osteoporosis.
Probenecid inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. It is able to prevent the efflux of calcium-sensitive fluor...
Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
DPY-2103 is a useful intermediate for chemical synthesis of a number of biologically active drugs.
Domiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant.
Benzyl alcohol, an aromatic alcohol compound, could be found in many sorts of essential oils with the FEMA number: 2137.
TAK-243, a pyrazolopyrimidine derivative, has been found to be an Ubiquitin-protein ligase inhibitor and was just finished the Phase-I trial against solid tumou...
2-Aminoheptane, a fatty Amine compound, is commonly used in proteomics research and could also be used to product some A3 adenosine receptor antagonists.