Duocarmycin SA - CAS 130288-24-3
Not Intended for Therapeutic Use. For research use only.
Category:
ADCs
Product Name:
Duocarmycin SA
Synonyms:
Cyclopropa(c)pyrrolo(3,2-e)indole-6-carboxylic acid, 1,2,4,5,8,8a-hexahydro-4-oxo-2-((5,6,7-trimethoxy-1H-indol-2-yl)carbonyl)-, methyl ester,
CAS Number:
130288-24-3
Description:
Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Molecular Weight:
477.47
Molecular Formula:
C25H23N3O7
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
COC1=C(C(=C2C(=C1)C=C(N2)C(=O)N3CC4CC45C3=CC(=O)C6=C5C=C(N6)C(=O)OC)OC)OC
InChI:
InChI=1S/C25H23N3O7/c1-32-17-6-11-5-14(26-19(11)22(34-3)21(17)33-2)23(30)28-10-12-9-25(12)13-7-15(24(31)35-4)27-20(13)16(29)8-18(25)28/h5-8,12,26-27H,9-10H2,1-4H3/t12-,25-/m1/s1
InChIKey:
VQNATVDKACXKTF-XELLLNAOSA-N
Tag:
ADCs Cytotoxin
Chemical Structure
CAS 130288-24-3 Duocarmycin SA

Related ADCs Cytotoxin Products


CAS 1005-93-2 Etbicuphat

Etbicuphat
(CAS: 1005-93-2)

Etbicuphat is a GABAa receptor antagonist known to cause convulsions, seizures and other neuromuscular related episodes. Used in the study of anti-epileptic dru...

CAS 79316-86-2 Tempidol hydrochloride

Tempidol hydrochloride
(CAS: 79316-86-2)

Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .

CAS 51424-33-0 alpha-Salsoline HCl

alpha-Salsoline HCl
(CAS: 51424-33-0)

Alkaloid, Tetrahydroisoquinoline, Active dopamine metabolite, Cholinesterase inhibitor

CAS 546-48-5 Pempidine tartrate

Pempidine tartrate
(CAS: 546-48-5)

Synthetic, a neuronal nicotinic AChR antagonist.

CAS 205304-86-5 Tubulysin A

Tubulysin A
(CAS: 205304-86-5)

Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...

Sevedindione

Sevedindione presents an antiarrhythmic activity on arrhythmias caused by Aconitine.

CAS 6681-13-6 Hernandezine

Hernandezine
(CAS: 6681-13-6)

Anti-tumor effect of hernandezine and other components extracted from Thalictrum glandulosissimum.

CAS 20069-05-0 Nitrarine 2HCl

Nitrarine 2HCl
(CAS: 20069-05-0)

Nitrarine 2HCl is a hypotensive, spasmolytic, coronary dilator, sedative in experimental arrhythmias.

CAS 86992-41-8 Lapidine

Lapidine
(CAS: 86992-41-8)

Carothane complex ester , from plants of the Umbelliferae family.

Acorine
(CAS: 110225-59-7)

A C20-diterpene alkaloid, reversible N-cholinoblocker A Diterpene alkaloid Isolated from the epigeal part ofAconitum coreanum.

CAS 21314-58-9 Triazolone HCl

Triazolone HCl
(CAS: 21314-58-9)

Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.

CAS 153720-49-1 3-beta-chloro-Imperialine

3-beta-chloro-Imperialine
(CAS: 153720-49-1)

Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi. A potent medium-lasting selective M2 muscarinic receptor antagonist.

CAS 22964-77-8 Dubinidine

Dubinidine
(CAS: 22964-77-8)

An anticonvulsant which reduces motor activity, enhances the effects of alcohol, ether and barbiturates. Quinoline alkaloid , from plants of the Rutaceae family...

CAS 21851-07-0 Diacetylkorseveriline

Diacetylkorseveriline
(CAS: 21851-07-0)

Diacetylkorseveriline is an antiarrhythmic (classes i and iv), belonging to a novel structural class. effective against arrhythmia caused by aconitine,CaCl2, el...

CAS 118-08-1 Beta-(-)-Hydrastine

Beta-(-)-Hydrastine
(CAS: 118-08-1)

Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family.

CAS 524-40-3 Ricinine

Ricinine
(CAS: 524-40-3)

Ricinine is an alkaloid extract from the seeds of the castor-oil plant (Ricinus communalis). Ricinine is a central nervous system stimulant that could potential...

Anthraniloyllycoctonine
(CAS: 22413-78-1)

A reversible myorelaxant and ganglioblocker Diterpenoid alkaloid Semi-Synthetic, from Methyllicoctonine isolated from Delphinium rotundifolium Afan. (Ranunculac...

CAS 480-39-7 Pinocembrin

Pinocembrin
(CAS: 480-39-7)

Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option i...

CAS 123948-87-8 Topotecan

Topotecan
(CAS: 123948-87-8)

Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...

Fisonate
(CAS: 132742-32-6)

An inhibitor of serine proteinases of broad spectrum.