Duocarmycin B1 - CAS 124325-93-5
Not Intended for Therapeutic Use. For research use only.
Category:
ADCs
Product Name:
Duocarmycin B1
Synonyms:
1H-Pyrrolo(3,2-f)quinoline-2-carboxylic acid, 8-bromo-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-((5,6,7-trimethoxy-1H-indol-2-yl)carbonyl)-, methyl ester, (2R-trans)-;
CAS Number:
124325-93-5
Description:
Duocarmycin B1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Molecular Weight:
588.40
Molecular Formula:
C26H26BrN3O8
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
N1(C[C@H](Cc2c3c(c(cc12)O)N[C@](C3=O)(C(=O)OC)C)Br)C(=O)c1[nH]c2c(c1)cc(c(c2OC)OC)OC
InChI:
InChI=1S/C26H26BrN3O8/c1-26(25(34)38-5)23(32)18-13-8-12(27)10-30(15(13)9-16(31)20(18)29-26)24(33)14-6-11-7-17(35-2)21(36-3)22(37-4)19(11)28-14/h6-7,9,12,28-29,31H,8,10H2,1-5H3/t12-,26+/m0/s1
InChIKey:
SUWUAMDOMCWKCL-GWQKEKGPSA-N
Tag:
ADCs Cytotoxin

Related ADCs Cytotoxin Products


CAS 60-38-8 3-Acetyl-Strophanthidin

3-Acetyl-Strophanthidin
(CAS: 60-38-8)

An ATPase inhibitor.

Et3N-Pr
(CAS: 13028-68-7)

Ganglioblocker Synthetic

FSP-2

Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised.

CAS 71963-77-4 Artemether

Artemether
(CAS: 71963-77-4)

Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria.

14-Benzoyltalatisamine Perchlorate

A selective blocker of the delayed rectifier K+ channel found in virtual screening

CAS 130288-24-3 Duocarmycin SA

Duocarmycin SA
(CAS: 130288-24-3)

Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.

CAS 66547-09-9 Ansamitocin P-3

Ansamitocin P-3
(CAS: 66547-09-9)

Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...

CAS 304-21-2 Harmaline

Harmaline
(CAS: 304-21-2)

Harmaline is a fluorescent psychoactive indole alkaloid from the group of harmala alkaloids and beta-carbolines. It is the partially hydrogenated form of harmin...

CAS 54527-84-3 Nicardipine Hydrochloride

Nicardipine Hydrochloride
(CAS: 54527-84-3)

Dihydropyridine calcium channel blocker. Antianginal; antihypertensive.

LTx-003

A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.

3-alpha-iodo-Imperialine

A cardioselective M2-cholinoblocking compound semi-synthetic derivative of Imperialine alkaloid Derived from base alkaloid Imperialine, isolated from the plant ...

CAS 65988-34-3 Alpha-Latrotoxin

Alpha-Latrotoxin
(CAS: 65988-34-3)

A latrotoxin is a high-molecular mass neurotoxin found in the venom of spiders of the genus Latrodectus (widow spiders). Latrotoxins are the main active compone...

CAS 101-31-5 (-)-Hyoscyamine

(-)-Hyoscyamine
(CAS: 101-31-5)

Hyoscyamine is a tropane alkaloid. It is a secondary metabolite found in certain plants of the family Solanaceae, non-selective antagonist at Muscarinic recepto...

Seco-Duocarmycin TM
(CAS: 1142188-60-0)

Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.

Dendrotoxin I
(CAS: 107950-33-4)

Dendrotoxin-I is a highly selective blocker of voltage-gated K+<br/>channels (KV1.1 and KV1.2), as well as heteromultimeric channels containing these, with othe...

CAS 163768-50-1 Auristatin F

Auristatin F
(CAS: 163768-50-1)

Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.

Sevedindione

Sevedindione presents an antiarrhythmic activity on arrhythmias caused by Aconitine.

CAS 16408-77-8 Thalicminine

Thalicminine
(CAS: 16408-77-8)

Alkaloid, extracted from Thalictrum isopyroide.

CAS 11033-64-0 N-deacetyllappaconitine

N-deacetyllappaconitine
(CAS: 11033-64-0)

A diterpenoid alkaloids from plants of the Aconitum and Delphinium species, selective blocker of the TTX-sensitive Na+ channel in the heart; potent antiarrhythm...

CAS 86408-17-5 Askendoside D

Askendoside D
(CAS: 86408-17-5)

Askendoside D presents a high selectivity for the cardiac Na+/K+-ATPase, with practically no activity on brain or kidney Na+/K+-ATPases, as compared with other ...