|Description||An anticonvulsant which reduces motor activity, enhances the effects of alcohol, ether and barbiturates. Quinoline alkaloid , from plants of the Rutaceae family.|
An analog of Veratridine; Na+ channel activator; potent neurotoxic; depolarizing agent on membranes of nerve terminal, muscle and gland cells.
A muscarinic receptors antagonist.
Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...
Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
A native alkaloid A tropane alkaloid Extracted from Convolvulus subhirsitus plant.
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influen...
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Lignan , from plants of the Rutaceae family, a substance presenting an estrogenic activity and sedative effects. .
A proanthocyanidin from Polygonum coriaricum, an antihypoxic.
Askendoside D presents a high selectivity for the cardiac Na+/K+-ATPase, with practically no activity on brain or kidney Na+/K+-ATPases, as compared with other ...
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus) venoms. A pre-synaptic toxin with enzymatic activity.
Synthetic, a selective irreversible inhibitor of carboxylesterases
Duocarmycin is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.
Scopolamine, a nonselective muscarinic receptor antagonist, induces distinct behaviors of attenuated motility and C-like hyperactivity.
Phencarol is used in the biological studies of azoniabicyclooctanes as muscarinic acetylcholine receptor antagonists.
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...
Synthetic, an inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Extractedfrom Vinca erecta. A dopamine receptor stimulating agent Indolinine alkaloid
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.