|Description||DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.|
Seco-Duocarmycin CN is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Photosensitizing; used for determining DNA/RNA structures in cells and microorganisms. Furocoumarin , from plants of the Psoralea genus, Leguminosae.
Seco-Duocarmycin DMA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
A cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by the sarcolemmal Ca2+/Mg2+-ATPas...
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
Synthetic, a weak AChR antagonist.
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostati...
DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
A Norditerpenoid alkaloid. Nicotinic receptor antagonist at the neuromuscular junction and vegetative ganglia; hypotensive. Diterpene alkaloid , from plants of ...
Fraxinellone is an insecticidal agent, inhibiting growth of larvae, used in the treatment and protection of crops and produce. Also, a naturally occurring compo...
Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
A cardioselective M2-cholinoblocking compound semi-synthetic derivative of Imperialine alkaloid Derived from base alkaloid Imperialine, isolated from the plant ...
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Daunorubicin(RP13057) inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.
Polyprenols are natural long-chain isoprenoid alcohols of the general formula H-(C5H8)n-OH where n is the number of isoprene units. Any prenol with more than 4 ...
Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi. A potent medium-lasting selective M2 muscarinic receptor antagonist.
Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...