DM1-SMe - CAS 138148-68-2
Not Intended for Therapeutic Use. For research use only.
Category:
ADCs
Product Name:
DM1-SMe
Synonyms:
DM1-SMe; DM1-SSMe; maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative; N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine.
CAS Number:
138148-68-2
Description:
DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. DM1-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). .
Molecular Weight:
784.38
Molecular Formula:
C36H50ClN3O10S2
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
C[C@@H]1[C@@H]2C[C@](NC(O2)=O)(O)[C@H](OC)/C=C\C=C(C)\CC3=CC(N(C)C(C[C@@H](OC([C@@H](N(C(CCSSC)=O)C)C)=O)[C@@]4(C)C1O4)=O)=C(Cl)C(OC)=C3
Tag:
ADCs Cytotoxin with Linkers

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