Tetrahydroberberine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Tetrahydroberber...
(Dap22)-ShK (ShK Dap22) peptide is a synthetic derivative of the well-known ShK toxin isolated from the venom of the Carribean sea anemone Stoichactis helianthu...
Terpenoids found in the umbelliferae family act as agonists/antagonists for ER(alpha) and Erbeta.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
An analog of Veratridine; Na+ channel activator; potent neurotoxic; depolarizing agent on membranes of nerve terminal, muscle and gland cells.
Diazoline is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.
Alkaloid, extracted from Thalictrum isopyroide.
An inhibitor of serine proteinases of broad spectrum.
α-Cobratoxin is a substance of the venom of certain Naja cobras. It is a nicotinic acetylcholine receptor (nAChR) antagonist which causes paralysis by preventin...
Deltaline has a lycoctonine carbon-atom skeleton with four six-membered rings and three five-membered rings among; three of the six-membered rings adopt chair c...
Auristatin F is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAF analog and cytotoxin in Antibody-drug conjugates.
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions relea...
A potent antiarrhytmic and local anesthetic. Alkaloid , from plants of the Ranunculaceae family. Inhibitorand Enhancers of Uridine Diphosphate-Glucuronosyltrans...
Synthetic., a GABA-gated chloride channel blocker, non-competitive GABA antagonist in mammals.
Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-a...
It was the main alkaloid found in medicinal plants Datura metel. .
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus) venoms. A pre-synaptic toxin with enzymatic activity.
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contamina...
Synthetic organophosphorous compound, a non-competitive GABA antagonist; potent convulsant: causes epileptoform seizures.
The lanthanide element from Glutaned replaces calcium in its complex with prothrombine,<br/>thus preventing the formation of thrombine and interrupting the bloo...