|Product Name||Dendrotoxin I|
|Description||Dendrotoxin-I is a highly selective blocker of voltage-gated K+
channels (KV1.1 and KV1.2), as well as heteromultimeric channels containing these, with other KV1 isoforms. The inhibition effect is higher in Xenopus oocytes compared to mammalian cells.
Synthetic, a selective irreversible inhibitor of carboxylesterases
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Seco-Duocarmycin DME is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Atropine is a medication used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production d...
Cyclopiazonic acid is a mycotoxin produced by molds including certain species of Penicillium and Aspergillus. Its toxicity is linked to its ability to specifica...
An ATPase inhibitor.
Diterpenoid alkaloids from the roots of Delphinium scabriflorum.
It was the main alkaloid found in medicinal plants Datura metel. .
Potent inhibitor of protein phosphatase tyoe 1 (PP1) and protein phosphatase tyoe 2A (PP2A).
Calciseptine is a natural neurotoxin isolated from the black mamba Dendroaspis p. polylepis venom. This toxin consists of 60 amino acids with four disulfide bon...
C19-norditerpenoid alkaloid , from plants of the Ranunculaceae family, a potent antiarrhythmic, antifibrillatory; Na+ channel blocker in cardiomyocytes.
A non-toxic, complement-activating component of cobra venom Three polypeptide chains with molecular masses of about 70, 50, and 30 kDa, the two large subunits b...
A native alkaloid A tropane alkaloid Extracted from Convolvulus subhirsitus plant.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Brevetoxin PbTx 1
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Polyprenols are natural long-chain isoprenoid alcohols of the general formula H-(C5H8)n-OH where n is the number of isoprene units. Any prenol with more than 4 ...
Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin ...
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q an...