Top Clicks This Month

Not Intended for Therapeutic Use. For research use only.

Daunorubicin Hydrochloride - CAS 23541-50-6

Quick Inquiry

Name:
* Email:
* Service & Products of Interest:
* Quantity:
* Verification code:
Please input "bocsci" as verification code.
Category
ADCs
Product Name
Daunorubicin Hydrochloride
Catalog Number
23541-50-6
Synonyms
RP 13057 Hydrochloride; Daunomycin; RP13057 Hydrochloride; RP-13057 Hydrochloride; Rubidomycin hydrochlorideE
CAS Number
23541-50-6
Description
Daunorubicin Hcl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.
Molecular Weight
563.98
Molecular Formula
C27H30ClNO10
COA
Inquire
MSDS
Inquire
Tag
ADCs Cytotoxin
Structure
CAS 23541-50-6 Daunorubicin Hydrochloride
Specification
Purity
>98%
Application
ADCs Cytotoxin
Related ADCs Cytotoxin Products
  • CAS 21829-25-4 Nifedipine

    Nifedipine
    (CAS: 21829-25-4)

    Used as an antihypertensive and antianginal. A dihydorpyridine calcium channel blocker.

  • [Tyr2] Scyllatoxin
    (CAS: )

    [Tyr2]-Scyllatoxin allows labelling by iodination. 31-amino acid polypeptide with 3 disulfide bridges. , synthetic, originally from Leiurus quinquestriatus hebr...

  • Seco-DuocarmycinDMG
    (CAS: 1613286-55-7)

    Seco-Duocarmycin DMG is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.

  • CAS 5489-15-6 O-Methylisocorydine Iodomethylate

    O-Methylisocorydine Iodomethylate
    (CAS: 5489-15-6)

    Aporphin alkaloid derivative of Isocorydine from plants of the Corydalis genus, Fumariaceae, a long-lasting ganglioblocker, with a sympathetic/parasympathetic a...

  • Dendrotoxin I
    (CAS: 107950-33-4)

    Dendrotoxin-I is a highly selective blocker of voltage-gated K+<br/>channels (KV1.1 and KV1.2), as well as heteromultimeric channels containing these, with othe...

  • CAS 62996-74-1 Staurosporine

    Staurosporine
    (CAS: 62996-74-1)

    Staurosporine is broad spectrum protein kinase inhibitor. Enzymes inhibited include protein kinase C (IC50 = 3 nM), protein kinase A (IC50 = 7 nM), p60v-src tyr...

  • CAS 87777-29-5 Morphiceptin

    Morphiceptin
    (CAS: 87777-29-5)

    Morphiceptin is a four amino acid peptide derived from the ß-casomorphin, a protein fragment itself derived from the digestion of milk protein casein. It is one...

  • CAS 54965-21-8 Albendazole

    Albendazole
    (CAS: 54965-21-8)

    An anthelmintic: blocks the enzymatic process responsible for the absorption of glucose by parasites, causing their death. Benzimidazole derivative , synthetic.

  • CAS 126-17-0 Solasodine

    Solasodine
    (CAS: 126-17-0)

    Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity agai...

  • CAS 66-97-7 Psoralen

    Psoralen
    (CAS: 66-97-7)

    Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function. It intercalates into DNA and, when activated by ultraviol...

  • H-Glutaned
    (CAS: 148822-93-9)

    The lanthanide element from Glutaned replaces calcium in its complex with prothrombine,<br/>thus preventing the formation of thrombine and interrupting the bloo...

  • FSP-1
    (CAS: )

    Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, identifies an inflammatory subpopulation of macrophages in...

  • Lqh III
    (CAS: 212134-01-5)

    A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.

  • CAS 60697-89-4 LK-190

    LK-190
    (CAS: 60697-89-4)

    A muscarinic receptors antagonist.

  • M4-Nitrodienamine
    (CAS: )

    Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.

  • M1-Nitrodienamine
    (CAS: 113418-72-7)

    Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.

  • CAS 142948-19-4 Scyllatoxin

    Scyllatoxin
    (CAS: 142948-19-4)

    Scyllatoxin (also leiurotoxin I) is a toxin, from the scorpion Leiurus quinquestriatus hebraeus, which blocks small-conductance Ca2+-activated K+ channels.

  • (-)-Scopolamine Perchlorate
    (CAS: )

    Scopolamine, a nonselective muscarinic receptor antagonist, induces distinct behaviors of attenuated motility and C-like hyperactivity.

  • CAS 7082-34-0 Erysimoside

    Erysimoside
    (CAS: 7082-34-0)

    Na+,K+-ATPase inhibiting activity of cardiac glycosides from Erysimum cheiranthoides

  • CAS 79580-28-2 Brevetoxin B

    Brevetoxin B
    (CAS: 79580-28-2)

    Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium c...

Reference Reading
1.Stability of [(N-pyrrolidine)metylene]daunorubicin in aqueous solutions
Anna Jeli ska, Justyna Uszak. React Kinet Catal Lett (2009) 98:69–75
The hydrolysis of [(N-Pyrrolidine)metylene]daunorubicin hydrochloride (PMD) involves: hydrolysis of protonated molecules of [(N-Pyrrolidine)metylene]daunorubicin hydrochloride (PMD) depending on hydrogen ions and spontaneous hydrolysis of zwitter, unprotonated and monoanions of [(N-Pyrrolidine)metylene]daunorubicin hydrochloride (PMD) under the influence of water. The components of phosphate, acetate and borate buffers do not demonstrate any catalytic effect. [(N-Pyrrolidine)metylene]daunorubicin hydrochloride (PMD) is the most stable at pH 2-4.
2.Administration of Chromium(III) and Manganese(II) as a Potential Protective Approach Against Daunorubicin-Induced Cardiotoxicity: in vitro and in vivo Experimental Evidence
Yang Liu & Debin Wang. Biol Trace Elem Res (2013) 156:253–261
Daunorubicin hydrochloride for injection was supplied by Pfizer Italia S.r.1. Cardiac myosin, prepared and determined according to the protocols of our previous study, was diluted to 0.4 μM with 0.01M Tris–HCl buffer saline (pH 7.4) containing 0.6 M KCl. CrCl3•6H2O and MnCl2•4H2O were purchased from Chinese Medicine (Group) Shanghai Chemical Reagent Company. Other chemical reagents weremade in China and were of analytical grades, and ultrapure water was used throughout the studies.
2005 - BOC Sciences | All rights reserved
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
BOCSciences
X CLOSE
DOWNLOAD