DAPT - CAS 208255-80-5
Not Intended for Therapeutic Use. For research use only.
Category:
Stem Cell Molecule
Product Name:
DAPT
Catalog Number:
208255-80-5
CAS Number:
208255-80-5
Description:
DAPT, a cell-permeable dipeptide, inhibits γ-secretase and indirectly inhibits Notch, a γ-secretase substrate. Since the Notch pathway is involved in the development of both the nervous system and pancreas, DAPT may be useful in modulating Notch activity in embryonic stem cell differentiation studies. DAPT has been shown to dose-dependently decrease amyloid-β levels via inhibition of γ-secretase in both plasma and cerebral spinal fluid3. Since amyloid-β containing senile plaques are characteristic in Alzheimer's disease, DAPT may be useful in studies evaluating potential treatments for that disease.
Molecular Weight:
432.46
Molecular Formula:
C23H26F2N2O4
COA:
Inquire
MSDS:
Inquire
Chemical Structure
CAS 208255-80-5 DAPT