Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
Quinoline Alkaloid Extracted from Haplophyllum bucharicum
DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
[Tyr2]-Scyllatoxin allows labelling by iodination. 31-amino acid polypeptide with 3 disulfide bridges. , synthetic, originally from Leiurus quinquestriatus hebr...
Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option i...
An antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematode...
Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone.
Sanguinarine is a toxic quaternary ammonium salt from the group of benzophenanthridine alkaloids. It is extracted from some plants, including bloodroot (Sanguin...
Gossypol Acetic Acid
an antiviral at low concentration; antiherpes, antipsoriasis and antikeratitis, male contraceptive. Polyphenol , from plants of the Gossypium genus, Malvaceae.
α-conotoxin MI (alpha-conotoxin MI) is a conotoxin that has been isolated from the venom of the cone snail Conus magus. α-conotoxin MI is a competitive antagoni...
Gramine is a naturally occurring indole alkaloid present in several plant species. Gramine may play a defensive role in these plants, since it is toxic to many ...
Long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Prevents β-amyloid-...
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.
An inhibitor of serine proteinases of broad spectrum.
Synthetic organophosphorous compound, a non-competitive GABA antagonist; potent convulsant: causes epileptoform seizures.