|Description||(Dap22)-ShK (ShK Dap22) peptide is a synthetic derivative of the well-known ShK toxin isolated from the venom of the Carribean sea anemone Stoichactis helianthus.|
Inhibitor of Ca2+/2H+-exchange system in liver mitochondria. , synthetic.
Scopolamine, a nonselective muscarinic receptor antagonist, induces distinct behaviors of attenuated motility and C-like hyperactivity.
Non-selective K+ channel blocker.
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Aconitine (AC), an active/toxic alkaloid from Aconitum species, is commonly present in Traditional Chinese Medicine (TCM) prescriptions because of the great eff...
Seco-Duocarmycin MB is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions relea...
Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
A cardioselective M2-cholinoblocking compound semi-synthetic derivative of Imperialine alkaloid Derived from base alkaloid Imperialine, isolated from the plant ...
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematode...
Seco-Duocarmycin CN is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q an...
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
Seco-Duocarmycin MA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic ...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Alkaloid , from plants of the Ranunculaceae family. Ganglioblocker; nicotinic receptor antagonist; hypotensive; presents micromolar affinity at brain a Bungarot...
A highly active peripheral M2-cholinoblocker alkaloid. Imperialine is extracted from Petilium eduardi and Petilium raddeanae (Liliaceae family)
Nemorubicin, is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity pro...