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D-FRUCTOSE 2,6-DIPHOSPHATE SODIUM SALT - CAS 84364-89-6

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Category
Main Product
Product Name
D-FRUCTOSE 2,6-DIPHOSPHATE SODIUM SALT
Catalog Number
84364-89-6
Synonyms
Sodium; [(2S,3S,4S,5R)-3,4-dihydroxy-2-phosphonooxy-5-(phosphonooxymethyl)oxolan-2-yl]methanolate; 84364-89-6; Sodium ((2S,3S,4S,5R)-3,4-dihydroxy-2-(phosphonooxy)-5-((phosphonooxy)methyl)tetrahydrofuran-2-yl)methanolate; AKOS024258631; AK151174; FT-0699619; ST24049169; D-FRUCTOSE 2,6-DIPHOSPHATE SODIUM SALT
CAS Number
84364-89-6
Description
D-FRUCTOSE 2,6-DIPHOSPHATE SODIUM SALT, whose free base is Fructose 2,6-bisphosphate. Fructose 2,6-bisphosphate is a phosphorylating agent regulate glycolysis and gluconeogenesis through allosterically affecting the activity of the enzymes phosphofructokinase 1 (PFK-1) and fructose 1,6-bisphosphatase (FBPase-1).
Molecular Weight
362.10
Molecular Formula
C6H13NaO12P2. x Na
Quantity
Grams-Kilos
Quality Standard
In-house Standard
COA
Certificate of Analysis-D-FRUCTOSE 2,6-DIPHOSPHATE SODIUM SALT 84364-89-6 B16Z01103  
MSDS
Inquire
Canonical SMILES
C(C1C(C(C(O1)(C[O-])OP(=O)(O)O)O)O)OP(=O)(O)O.[Na+]
InChI
1S/C6H13O12P2.Na/c7-2-6(18-20(13,14)15)5(9)4(8)3(17-6)1-16-19(10,11)12;/h3-5,8-9H,1-2H2,(H2,10,11,12)(H2,13,14,15);/q-1;+1/t3-,4-,5+,6+;/m1./s1
InChIKey
UAGLXYBMOWLLDI-QAYODLCCSA-N
Structure
CAS 84364-89-6 D-FRUCTOSE 2,6-DIPHOSPHATE SODIUM SALT
Specification
Appearance
White crystal powder
Application
An essential phosphorylating agent for glucose-regulated gene transcription and other ChREBP target genes in hepatocytes
Solubility
Easily soluble in water, insoluble in CHCl3
Reference Reading
1.Sodium d-fructose-1,6-diphosphate vs. sodium monohydrogen phosphate in total parenteral nutrition: a comparative in vitro assessment of calcium phosphate compatibility.
Prinzivalli M1, Ceccarelli S. JPEN J Parenter Enteral Nutr. 1999 Nov-Dec;23(6):326-32.
BACKGROUND: The supply of high amounts of calcium (Ca) and phosphorus (P) during total parenteral nutrition (TPN) is matter of concern because of the risk associated with calcium phosphate precipitation. The in vitro Ca-P compatibility in ready-for-use TPN solutions after the addition of different concentrations of inorganic phosphate or d-fructose-1,6-diphosphate (FDP) and calcium chloride was evaluated.
2.4-hydroxy-2,5-dimethyl-3(2H)-furanone formation by Zygosaccharomyces rouxii: effect of the medium.
Hauck T1, Brühlmann F, Schwab W. J Agric Food Chem. 2003 Jul 30;51(16):4753-6.
The formation of 4-hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF) by Zygosaccharomyces rouxii was studied in yeast-peptone-dextrose medium containing d-fructose 1,6-diphosphate under various culture conditions. Cell growth and HDMF production was heavily dependent on medium pH and sodium chloride concentration. Higher pH values of the nutrient medium had a positive effect on HDMF formation but retarded cell growth resulting in an optimal pH value of 5.1 with regard to the yield of HDMF. Salt stress stimulated HDMF formation by Z. rouxii as increasing sodium chloride concentration led to higher amounts of HDMF. The HDMF concentration in the culture supernatant and HDMF formation per yeast cell peaked at 20% sodium chloride in the nutrient medium. The nonutilizable carbohydrate d-xylose displayed a weak effect on HDMF formation, and the addition of glycerol to salt-stressed cells had no effect on the production of HDMF.
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