Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
An antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
Lignan , from plants of the Rutaceae family, a substance presenting an estrogenic activity and sedative effects. .
A latrotoxin is a high-molecular mass neurotoxin found in the venom of spiders of the genus Latrodectus (widow spiders). Latrotoxins are the main active compone...
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
Duocarmycin is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Estrogenic activity; half agonist of estradiol receptors. Complex esters of phenolcarbon acids, , from plants of the Ferula genus, Umbelliferae.
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contamina...
Synthetic, a weak AChR antagonist.
Synthetic, an inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions relea...
An inhibitor of MAO.
Derivative of Napelline. Napelline isolated from plant Aconitum karakolicum Diterpenoid Alkaloid Synthesized from Napelline. Napelline is extracted from Aconitu...
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q an...
Photosensitizing; used for determining DNA/RNA structures in cells and microorganisms. Furocoumarin , from plants of the Psoralea genus, Leguminosae.
A highly active peripheral M2-cholinoblocker alkaloid. Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi.
Steroidal Alkaloid Derivative of Imperialine extracted from Petilium eduardi, a medium-lasting and selective M2 muscarinic receptors antagonist.
Ryanodine High Purity
Potent inhibitor of Ca2+ release from sarcoplasmic reticulum
Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibits microtubule assembly.
Lycoctonine is a plant alkaloid and a precursor to the ABC ring system of taxoids.