|Synonyms||S-(-)-Cotinine; (5S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone; (S)-(-)-1-Methyl-5-(3-pyridiyl)-2- pyrrolidinone;|
|Description||A carcinogen as a a major metabolite of Nicotine in humans.|
|Quality Standard||Enterprise Standard|
GNE-3500 has been found to be a Retinoic acid receptor-related Orphan receptor C agonist that could be probably significant in studies of some inflammatory dise...
GSK2256294A, an effective inhibitor of human soluble epoxide hydrolase(sEH), was developed by GSK and still under Phase I trial in Chronic obstructive pulmonary...
XCT 0315908, a RXR agonist, showed selectivity for RXR−Nurr1 over a broad range of other RXR dimerization partners but with rather low potency.
STING agonist; Induces antitumor immunological responses
Epothilone F, an active metabolite of Epothilone D, prevents cancer cells from dividing by interfering with tubulin.
Hybendazole hydrochloride is a synthetic bio-active chemical.
Isoalantolactone has the capacity to inhibit tumor cell growth through induction of apoptosis.
Deferoxamine mesylate, an iron chelator, could be used in the treatment of acute iron poisoning, sickle cell diseases and it is also found to have some extent o...
NADPH tetrasodium salt
NADPH tetrasodium salt is an ubiquitous coenzyme that acts as an electron donor in various biological reactions.
4-Methylbenzylidene camphor (4-MBC) is an organic camphor derivative that is used in the cosmetic industry for its ability to protect the skin against UV, speci...
BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression.
CBR 5884 is a 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50 = 33 μM), does not affect other NAD+-dependent dehydrogenases.
SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibit...
Santacruzamate A (CAY10683) is a potent and selective HDAC inhibitor with IC50 of 119 pM for HDAC2, >3600-fold selectivity over other HDACs.
CI-959 free acid
CI-959 free acid is an orally effective inhibitor of cellular activation in both in vitro and animal models. It has antiallergic and anti-inflammatory propertie...
GKT137831 attenuates hypoxia-induced H(2)O(2) release, cell proliferation, and TGF-β1 expression and blunted reductions in PPARγ in HPAECs and HPASMCs.
AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor and showed no inhibition or stimulation of >50% at 10μM in a standard selectivity panel of...
(+/-)-alpha-Lipoamide is a coenzyme, which transfer acetyl and hydrogen in Pyruvate deacylation oxidation process. It may be used in treatment of insulin resist...
Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infesta...
Tetrahydrocurcumin is being studied for the treatment of cancer and dementia. It has antioxidant and anti-inflammatory properties. Tetrahydrocurcumin has been s...