|Description||Condelphine was isolated from the roots of Delphinium denudatum. A nicotinic receptor antagonist at the neuromuscular junction and ganglioblocking agent.|
Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumven...
hypotensive, central adrenolytic Semisynthetic derivative of natural alkaloid Galantamine Extracted from Ungernia Victoris (Amarillidaceae Fam.)
It was the main alkaloid found in medicinal plants Datura metel. .
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activ...
Tubulysin M is a Tubulysin D analog with potential anti-cancer properties, used as the cytotoxic component in antibody-drug conjugates.
ω-conotoxin MVIIC (omega conotoxin MVIIC) is a conotoxin that has been isolated from the venom of the cone Conus magus. ω-conotoxin MVIIC is a blocker of P/Q an...
Tschimgine a substance presenting an estrogenic activity..
Etbicuphat is a GABAa receptor antagonist known to cause convulsions, seizures and other neuromuscular related episodes. Used in the study of anti-epileptic dru...
Chlorotoxin (Cltx) is a neurotoxin that was originally isolated from the venom of Leiurus quinquestriatus. Chlorotoxin is a specific ligand of glioma cells. Chl...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Kaliotoxin (1-37)NH2 is a selective voltage-dependent K+ channels blocker, a blocker of Ca2+-activated K+ channels of high conductance and some voltage-dependen...
AChR agonist. Rigid bicyclic analog of ACh and ARECOLINE. Good penetration of biological membranes. Quinuclidine derivative, , synthetic.
Selective blocker of the big conductance Ca2+-activated K+ channel.
Triterpene glycoside Extracted from Dipsacus azureas
An inhibitor of serine proteinases of broad spectrum.
Extract from plants of the Leguminosae family, an antiatherosclerotic and angioprotective, reduces platelet aggregation.
An inhibitor of the binding of [125I]-apamin to rat brain synaptosomes and a specific neurotoxicity in mice<br/>A 31 Amino-Acids peptide with 3 disulfide bonds ...
Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised.
Staurosporine is broad spectrum protein kinase inhibitor. Enzymes inhibited include protein kinase C (IC50 = 3 nM), protein kinase A (IC50 = 7 nM), p60v-src tyr...
Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.