Bicyclic diterpenoid of the clerodane series
Diamine oxidase activator. Na+ channels blocker.
DM 4 is an intermediate used to prepare semisynthetic maytansine analogs which can be conjugated with antibodies for the targeted treatment of cancer.
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
A spasmolytic agent, shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.
Calciseptine is a natural neurotoxin isolated from the black mamba Dendroaspis p. polylepis venom. This toxin consists of 60 amino acids with four disulfide bon...
Brevetoxin PbTx 1
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.
Synthetic, a neuronal nicotinic AChR antagonist.
Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular rel...
Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
A muscarinic receptors antagonist.
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and pr...
Ducamycin Analog is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Askendoside D presents a high selectivity for the cardiac Na+/K+-ATPase, with practically no activity on brain or kidney Na+/K+-ATPases, as compared with other ...
An analog of Veratridine; Na+ channel activator; potent neurotoxic; depolarizing agent on membranes of nerve terminal, muscle and gland cells.
Nemorubicin, is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity pro...
Rebaudioside A is a glycoside from the stevia plant. Rebaudioside A is used as a sweetener with sweetness about 300 times that of sugar with negligible effect o...