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Colchicine - CAS 64-86-8

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Category
ADCs
Product Name
Colchicine
Catalog Number
64-86-8
Synonyms
N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide; Colchicine; Colchicine, (+-)-Isomer; Colchicine, (R)-Isomer
CAS Number
64-86-8
Description
Colchicine, a toxic plant-derived alkaloid extracted from plants of the genus Colchicum, inhibits microtubule polymerization (IC50 = 3.2 μM).
Molecular Weight
399.44
Molecular Formula
C22H25NO6
COA
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MSDS
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Canonical SMILES
CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC
InChI
1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
InChIKey
IAKHMKGGTNLKSZ-INIZCTEOSA-N
Targets
Microtubule/Tubulin
Structure
CAS 64-86-8 Colchicine
Specification
Melting Point
142-150ºC
Appearance
White solid
Storage
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -52℃ for long term (months to years).
Solubility
Soluble to 100 mM in water and to 100 mM in DMSO
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