Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...
Bicyclic diterpenoid of the clerodane series
Synthetic.alkaloid, a neuronal nicotinic AChR antagonist. Ganglioblocker.
Harmaline is a fluorescent psychoactive indole alkaloid from the group of harmala alkaloids and beta-carbolines. It is the partially hydrogenated form of harmin...
DC-1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
C20-diterpenoid alkaloid from plants of the Aconitum genus, Ranunculaceae. Adrenergic and Serotonergic stimulant; CNS stimulant; antiarrhythmic.
Amaryllidaceae alkaloid from plants of the Amaryllidaceae family. A hypotensive, sedative. Amaryllidaceae alkaloid , from plants of the Amaryllidaceae family.
Is any neutral chemical compound with a positively charged cationic functional group such as a quaternary ammonium or phosphonium cation which bears no hydrogen...
A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.
ShK – Stichodactyla toxin
ShK (Stichodactyla helianthus Neurotoxin) has been isolated from the venom of the Carribean sea anemone Stoichactis helianthus. ShK inhibits voltage-dependent p...
Methimazole inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone synthesis by oxidizing the anion iodide (I−) to iodine (I2), hypoiodous ...
Seco-Duocarmycin DME is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL.
Ansamitocin P-3, a potent anti-tumor maytansinoid found in Actinosynnema pretiosum, is a maytansine analog which displays potent cytotoxicity against the human ...
Estrogenic activity; half agonist of estradiol receptors. Complex esters of phenolcarbon acids, , from plants of the Ferula genus, Umbelliferae.
Notexin exerts both presynaptic (blocks the release of acetylcholine) and myotoxic<br/>activities
PBD dimer is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
An inhibitor of the binding of [125I]-apamin to rat brain synaptosomes and a specific neurotoxicity in mice<br/>A 31 Amino-Acids peptide with 3 disulfide bonds ...
Synthetic, a neuronal nicotinic AChR antagonist.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.