cinnamyl butyrate - CAS 103-61-7
Catalog number: 103-61-7
Category: Main Product
Molecular Formula:
C13H16O2
Molecular Weight:
204.26
COA:
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Purity:
95%
Appearance:
Colourless to yellowish liquid, fruity slightly floral balsamic odour
Synonyms:
TRANS-CINNAMYL BUTYRATE; 3-PHENYLALLYL BUTYRATE; 3-PHENYL-2-PROPEN-1-YL BUTYRATE; FEMA 2296; CINNAMYL BUTYRATE; CINNAMYL N-BUTYRATE; (2E)-3-Phenyl-2-propenyl butyrate; Butanoicacid,3-phenyl-2-propenylester
MSDS:
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Quantity:
Data not available, please inquire.
Boiling Point:
313.2ºC at 760 mmHg
Density:
1.013 g/mL at 25 °C(lit.)
1.Olfactory sensitivity during the menstrual cycle.
Mair RG, Bouffard JA, Engen T, Morton TH. Sens Processes. 1978 Jun;2(2):90-8.
Women were tested for sensitivity to several odorants at ovulation and menstruation. Three involatile esters (pentadecalactone, coumarin, and cinnamyl butyrate) predicted by gas chromatographic data to be strongly retarded by the olfactory mucus showed similar significant changes in sensitivity. By contrast, a more volatile ester (amyl acetate) predicted to diffuse more readily though the mucus showed no such changes. This suggests that variations in olfactory sensitivity observed between ovulation and menstruation depend on odorant volatility and thus may result from peripheral mechanisms limiting the access of odorant molecules to the olfactory receptors.
2.Fragrance material review on cinnamyl isobutyrate.
Bhatia SP1, Wellington GA, Cocchiara J, Lalko J, Letizia CS, Api AM. Food Chem Toxicol. 2007;45 Suppl 1:S74-7. Epub 2007 Sep 14.
A toxicologic and dermatologic review of cinnamyl isobutyrate when used as a fragrance ingredient is presented.
3.Fragrance material review on cinnamyl butyrate.
Bhatia SP1, Wellington GA, Cocchiara J, Lalko J, Letizia CS, Api AM. Food Chem Toxicol. 2007;45 Suppl 1:S62-5. Epub 2007 Sep 14.
A toxicologic and dermatologic review of cinnamyl butyrate when used as a fragrance ingredient is presented.
4.Differential regulation of human cathelicidin LL-37 by free fatty acids and their analogs.
Jiang W1, Sunkara LT, Zeng X, Deng Z, Myers SM, Zhang G. Peptides. 2013 Dec;50:129-38. doi: 10.1016/j.peptides.2013.10.008. Epub 2013 Oct 18.
LL-37 is the single cathelicidin host defense peptide in humans with direct antimicrobial and immunomodulatory activities. Specific regulation of LL-37 synthesis has emerged as a novel non-antibiotic approach to disease control and prevention. Short-chain fatty acids, and butyrate in particular, were found recently to be strong inducers of LL-37 gene expression without causing inflammation. Here, we further evaluated the LL-37-inducing efficiency of a broad range of saturated free fatty acids and their derivatives in human HT-29 colonic epithelial cells and U-937 monocytic cells by real-time RT-PCR. Surprisingly, we revealed that valerate, hexanoate, and heptanoate with 5-7 carbons are more potent than 4-carbon butyrate in promoting LL-37 gene expression in both cell types. Free fatty acids with longer than 7 or shorter than 4 carbons showed only a marginal effect on LL-37 expression. Studies with a series of fatty acid derivatives with modifications in the aliphatic chain or carboxylic acid group yielded several analogs such as benzyl butyrate, trans-cinnamyl butyrate, glyceryl tributyrate, and phenethyl butyrate with a comparable LL-37-inducing activity to sodium butyrate.
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CAS 103-61-7 cinnamyl butyrate

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