|Description||Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.|
A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.
Extract from plants of the Leguminosae family, an antiatherosclerotic and angioprotective, reduces platelet aggregation.
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic ...
Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin ...
Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells.
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influen...
Batrachotoxin (BTX) is an extremely potent cardiotoxic and neurotoxic steroidal alkaloid found in certain species of frogs, melyrid beetles, and birds.Batrachot...
Harmaline is a fluorescent psychoactive indole alkaloid from the group of harmala alkaloids and beta-carbolines. It is the partially hydrogenated form of harmin...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1....
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate.
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab ma...
A diterpenoid alkaloids from plants of the Aconitum and Delphinium species, selective blocker of the TTX-sensitive Na+ channel in the heart; potent antiarrhythm...
Beta- Belladonnine dichloroethylate
a short-acting muscle relaxant, twice as active as d-tubocurarine; possessing M2- and N- cholinolytic properties; also presenting antihistaminic activity. Tropa...
Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family.
Non-selective K+ channel blocker.
Extracted from Haplophyllum perforatum plant (Rutaceae fam.). An antiarrhythmic of first class Quinoline alkaloid