|Description||Synthetic, a selective irreversible inhibitor of carboxylesterases|
Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria.
A cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by the sarcolemmal Ca2+/Mg2+-ATPas...
Non-selective K+ channel blocker.
Alkaloid, extracted from Thalictrum isopyroide.
Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is com...
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate.
An inhibitor of MAO.
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contamina...
Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1....
AChR agonist. Rigid bicyclic analog of ACh and ARECOLINE. Good penetration of biological membranes. Quinuclidine derivative, , synthetic.
Tropane Alkaloid Extracted from Convolvulus subhirsutus
A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.
Potent antagonist for α7-containing neuronal nicotinic receptors (Ki = 1.4 nM). Interacts with α4β2 and α6β2 receptors at concentrations > 40 nM. Attenuates MET...
Daun02 is a daunorubicin b-galactoside prodrug for use in conjunction.
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple ...
Quinoline alkaloid , from plants of the Rutaceae family, an anticonvulsant; causes hypothermia; inhibits the reaction of orientation; prevents cardiac arrhythmi...
Synthetic, a selective irreversible inhibitor of carboxylesterases
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.