Biosynthesis of Chemicals

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The maturing petroleum-based chemical industry, the pressures of environmental constraints and the explosive development of biotechnology have increased the interest in catalysis in enzymology. Enzymes are now an attractive proposition as catalysts for new classes of reagents and products, especially sugars, chiral synthons, metabolites and food components.

Sometimes it is really hard to obtain the desired product from chemistry synthesis, especially when the scheme is very long. The best way to solve the problem is enzyme synthesis, semi-enzyme synthesis or fermentation.

Enzymes are the proteins which catalyse reactions in living cells and they have evolved to cope with specific tasks in biosynthetic or metabolic reactions. One of the biggest advantage of using enzyme in organic synthesis is the good selectivity. With enzymes, enantioselectivities of 99%+ e.e. can be achieved when synthesis the chiral compounds. In addition, when catalyzed by enzymes, the reaction are usually performed at mild conditions (dilute aqueous solution at less than 50°C), which makes the synthesis more convenient for users and environmentally friendly. All these advantages have been tailored to meet the needs of a diverse customer base with varying requirements at different stages of R&D and product commercialization. 

BOC Sciences has rich experience in these area and are happy to serve our customer who need it. Also, BOC Sciences provides a broad range of enzymes which can be used in pharmaceutical industry and other area by offering optionality in scale, scope and project complexity. Please find some examples of enzyme reactions:

Please do not hesitate to contact us if you want to know more about our service. Part of our products are listed as below:

O. Illudens
Rhizopus sp.
Adenylosuccinate synthase
Mitomycin C
Bacillus
Nonomuraea
Streptomyces
Pseudonocardia
Escherichia coli
Saccharomyces cerevisiae
Bacillus subtilis
Staphylococcus aureus
Klebsiella pneumoniae
Bacillus megaterium
Bacillus amyloliquefaciens
Corynebacterium glutamicum
Bacillus methylotrophicus
Geobacillus stearothermophilus
Nocardia
Micromonospora
Amycolatopsis
Kribbella
Rhodococcus
Pseudomonas
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