|Description||A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.|
DM 4 is an intermediate used to prepare semisynthetic maytansine analogs which can be conjugated with antibodies for the targeted treatment of cancer.
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
A cardioselective M2-cholinoblocking compound semi-synthetic derivative of Imperialine alkaloid Derived from base alkaloid Imperialine, isolated from the plant ...
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone m...
Lqh alpha IT Recombinant
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
Ganglioblocker Quaternary triethylamine derivative Synthetic
Synthetic, an inhibitor of monoamine oxydase.Enhances the toxicity of the Phenamine group and of Tryptamine.
Cloflubicyne is a potent non-competitive GABA antagonist, convulsant, laboratory insecticide.
An anesthetic acting on the nerve endings, with a good selectivity on sensory nerves; lowers arterial pressure; vasodilator. Tropane alkaloid , from plants of t...
An antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
A highly active peripheral M2-cholinoblocker alkaloid. Imperialine is extracted from Petilium eduardi and Petilium raddeanae (Liliaceae family)
Brevetoxin PbTx 1
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Tropane alkaloid, from plants of the Convolvulus genus,
α-conotoxin GI (alpha-conotoxin GI) is a conopeptide that has been isolated from the venom of the cone snail Conus geographus. α-conotoxin GI is a competitive a...
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...
A reversible myorelaxant and ganglioblocker Diterpenoid alkaloid Semi-Synthetic, from Methyllicoctonine isolated from Delphinium rotundifolium Afan. (Ranunculac...