Avibactam Sodium Salt - CAS 1192491-61-4
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
Avibactam Sodium Salt
Synonyms:
sulfuric acid mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester sodium salt (1:1); Sulfuric Acid Mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] Ester Sodium Salt; NXL 104
CAS Number:
1192491-61-4
Related CAS:
1192500-31-4 ( Avibactam free acid)
Description:
Avibactam Sodium Salt, a novel non-ᵦ-lactam ᵦ-lactamase inhibitor, binds covalently to Ambler class A ᵦ-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens.
Molecular Weight:
287.23
Molecular Formula:
C7H10N3NaO6S
COA:
Certificate of Analysis-Avibactam Sodium Salt 1192491-61-4 B16MW03281  
MSDS:
Inquire
Canonical SMILES:
NC([C@H]1[N@@](C2)C(N(OS([O-])(=O)=O)[C@@H]2CC1)=O)=O.[Na+]
InChI:
1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
InChIKey:
RTCIKUMODPANKX-JBUOLDKXSA-M
Targets:
Antibacterial
Current Developer:
Allergan; AstraZeneca; Cerexa; Novexel; Pfizer
Size Price Stock Quantity
500 mg $299 In stock
Bulk Inquiry
Chemical Structure
CAS 1192491-61-4 Avibactam Sodium Salt

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