Trichodesmine is a pyrrolizidine alkaloid that has neurotoxic effects and is naturally found in Crotolaria argyptiaca, a shrub plant that is native to the south...
Duocarmycin is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
A microtubule-disrupting agent.
Polyprenols are natural long-chain isoprenoid alcohols of the general formula H-(C5H8)n-OH where n is the number of isoprene units. Any prenol with more than 4 ...
Quinoline alkaloid, extracted from Haplophyllum bucharicum (Rutacae)
Seco-Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin
α-Dendrotoxin inhibits 4-AP sensitive, inactivating voltage-gated<br/>K+ channels (KV1.1, KV1.2 and KV1.6).
Ducamycin Analog is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
β-Pompilidotoxin slows the inactivation of neuronal Navs. β-Pompilidotoxin was isolated from the venoms of two wasps, Anoplius amariensis and Batozonellus macul...
Na+,K+-ATPase inhibiting activity of cardiac glycosides from Erysimum cheiranthoides
Ca2+-Activated K+ Channel Blocker
An ATPase inhibitor.
Brevetoxin PbTx 1
An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis....
Alkaloid, Tetrahydroisoquinoline, Active dopamine metabolite, Cholinesterase inhibitor
PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compa...
An antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
Cobra Venom Factor
A non-toxic, complement-activating component of cobra venom Three polypeptide chains with molecular masses of about 70, 50, and 30 kDa, the two large subunits b...
Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibits microtubule assembly.
Talatisamine inhibits the enhanced I(K) caused by Aβ40 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss ...