Staurosporine is broad spectrum protein kinase inhibitor. Enzymes inhibited include protein kinase C (IC50 = 3 nM), protein kinase A (IC50 = 7 nM), p60v-src tyr...
Diterpenoid Alkaloid Extracted from Aconitum orientale
an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
α-conotoxin MI (alpha-conotoxin MI) is a conotoxin that has been isolated from the venom of the cone snail Conus magus. α-conotoxin MI is a competitive antagoni...
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Conantokin-G is a conopeptide that has been isolated from the venom of the cone Conus geographus. Conantokin-G selectively inhibits NR2B containing N-methyl-D-a...
Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is com...
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
Na+,K+-ATPase inhibiting activity of cardiac glycosides from Erysimum cheiranthoides
A Norditerpenoid alkaloid. Nicotinic receptor antagonist at the neuromuscular junction and vegetative ganglia; hypotensive. Diterpene alkaloid , from plants of ...
Tropane alkaloid, from plants of the Convolvulus genus,
Potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1 and 25 nM for KV1.3, KV1.1 and KV1.2 channels) respectively). Also inhibits Ca2+-activ...
Non-selective K+ channel blocker.
Doxorubicin(Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
A cytostatic substance Isotryptamine.
Protopine is a benzylisoquinoline alkaloid occurring in opium poppy, Corydalis tubers and other plants of the family papaveraceae, like Fumaria officinalis. It ...
Bicyclic analog of Ach, a weak muscarinic AChR agonist.
Diterpenoid , from plants of the Stevia genus, Compositae. Sweetener; reported as possessing anti-hypertensive effects upon hypertensive rats.
Synthetic, GABAA-gated Cl- channels blocker; non-competitive GABAA antagonist.
Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants includ...