Margatoxin (MgTx) is a component of the venom of Scorpio Centruroides margaritatus. Margatoxin preferentially inhibits voltage-dependent potassium channels Kv1....
A native alkaloid A tropane alkaloid Extracted from Convolvulus subhirsitus plant.
Amiloride HCl is a relatively selective inhibitor of the epithelial sodium channel, used in the management of hypertension and congestive heart failure.
GABA receptor antagonist
Taltobulin trifluoroacetate (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
SNX-482 has been isolated from the venom of the Spider Hysterocrates gigas (African tarantula). SNX-482 modulates the R-type current associated with the class α...
Seco-Duocarmycin CN is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Dantrolene sodium is a postsynaptic muscle relaxant that lessens excitation-contraction coupling in muscle cells. It achieves this by inhibiting Ca2+ ions relea...
C20-diterpenoid alkaloid , from the Ranunculaceae family,an antiarrhythmic.
Synthetic, a weak AChR antagonist.
Na+,K+-ATPase inhibiting activity of cardiac glycosides from Erysimum cheiranthoides
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Hyoscyamine is a tropane alkaloid. It is a secondary metabolite found in certain plants of the family Solanaceae, non-selective antagonist at Muscarinic recepto...
Lycoctonine is a plant alkaloid and a precursor to the ABC ring system of taxoids.
A microtubule-disrupting agent.
Beta- Belladonnine dichloroethylate
a short-acting muscle relaxant, twice as active as d-tubocurarine; possessing M2- and N- cholinolytic properties; also presenting antihistaminic activity. Tropa...
A muscarinic receptors antagonist.
Sesquiterpene lactone , from plants of the Compositae family, an antiatherosclerotic, angioprotective, hypolipidemic and anti-inflammatory.
Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
DM 4 is an intermediate used to prepare semisynthetic maytansine analogs which can be conjugated with antibodies for the targeted treatment of cancer.