|Description||Artemisinin is a natural product originally isolated from plants of the genus Artemisia. It effectively kills malarial parasites of the genus Plasmodium. It is usually used in combination therapy for the treatment of malaria. Artemisinin is also used against a wide range of trematodes, including Schistosoma.|
Calciseptine is a natural neurotoxin isolated from the black mamba Dendroaspis p. polylepis venom. This toxin consists of 60 amino acids with four disulfide bon...
PF-06380101 is a novel cytotoxic Dolastatin 10 analogue; with excellent potencies in tumor cell proliferation assays and differential ADME properties when compa...
Combretastatin A4, under the IUPAC name 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol, inhibits tubulin polymerization (IC50= 2.2 μM). It has demons...
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins sh...
Diacetylkorseveriline is an antiarrhythmic (classes i and iv), belonging to a novel structural class. effective against arrhythmia caused by aconitine,CaCl2, el...
Tetrazoline HCl is a blocker of muscarinic cholinoreceptors located in isolated small intestine section.
Tschimgine a substance presenting an estrogenic activity..
Nudicauline is extracted from plants of the Ranunculaceae family, a Alpha-Bungarotoxin neuronal nicotinic receptor.
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. ...
A neuronal nicotinic AChR antagonist, blocking superior cervical sympathetic ganglion
A Na+ channel blocker; potent antiarrhythmic, inhibits voltage-gated Na+ channels in rat brain synaptosomes.
Artemether is an antimalarial for the treatment of multiple drug-resistant strains of Plasmodium falciparum malaria.
Synthetic, a selective irreversible inhibitor of carboxylesterases
An inhibitor of the binding of [125I]-apamin to rat brain synaptosomes and a specific neurotoxicity in mice<br/>A 31 Amino-Acids peptide with 3 disulfide bonds ...
Napelline is a diterpenoid alkaloid from plants of the Aconitum,genus, a potent antiarrhythmic with weak hypotensive and N-cholinoblocking effects.
Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.
A muscarinic receptors antagonist.
Alkaloid from reticuline and is a precursor of berberine.It has also been found to be a GABAA receptor agonist.
A natural compound extracted from Phellodendron chinense, exhibits a near planar framework