Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostati...
Synthetic, nicotinic AChR. Rigid bicyclic analog of TMA and TEA.
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone m...
A latrotoxin is a high-molecular mass neurotoxin found in the venom of spiders of the genus Latrodectus (widow spiders). Latrotoxins are the main active compone...
A natural compound extracted from Phellodendron chinense, exhibits a near planar framework
Daunorubicin(RP13057) inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.
Scyllatoxin (also leiurotoxin I) is a toxin, from the scorpion Leiurus quinquestriatus hebraeus, which blocks small-conductance Ca2+-activated K+ channels.
Extracted from Haplophyllum perforatum plant (Rutaceae fam.). An antiarrhythmic of first class Quinoline alkaloid
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
Diplacine is a nicotinic cholinoreceptor antagonist at the neuromuscular junction.
Diterpenoid , from plants of the Stevia genus, Compositae. Sweetener; reported as possessing anti-hypertensive effects upon hypertensive rats.
Cynaroside is a flavone, a flavonoid-like chemical compound. It is a 7-O-glucoside of luteolin.
Long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Prevents β-amyloid-...
DM1 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised.
Hydrobromide salt of (+)-Lappaconitine, a potential antitumor agent agent that induces HL-60 differentiation and apoptosis with analgesic activity as well.
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate.
An antineoplastic alkaloid from Colchicum autumnale L. isolated from Colchicum autumnale L.
Cloflubicyne is a potent non-competitive GABA antagonist, convulsant, laboratory insecticide.
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.