|Product Name||Alosetron-d3 Hydrochloride|
|Synonyms||2,3,4,5-Tetrahydro-5-(methyl-d3)-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride; GR 68755-d3; GR 68755X-d3; Lotronex-d3|
|Description||The hydrochloride salt form of isotope labelled Alosetrone which is a 5HT3-receptor antagonist and could be effective against irritable bowel syndrome.|
Almotriptan Malate is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.
Sarpogrelate is a drug under the development of Mitsubishi Chemical as 5HT2A and 5-HT2B receptor. antagonists. It is used as an antiplatelet agent and has been ...
Dolasetron, a pseudopelletierine derivative, is a 5-HT3 receptor antagonist that could be used to relieve the nausea and vomiting caused by chemotherapy.
The tosylate salt form of Lumateperone which is an highly effective antagonist of 5-HT2A receptor, could be used against insomnia. IC50: 0.54 nM(Ki).
LY 344864 is a brain penetrant, full agonist that specifically targets 5-HT1F receptor (pKi = 8.2) with > 80-fold selectivity over other serotonin receptors (Ki...
(R)-6-Hydroxybuspirone is a major active metabolite of Buspirone. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the ...
Thesuccinate salt form of Frovatriptan, a carbazole derivative, has been found to be a 5-HT receptor agonist that could be used as an antimigraine agent.
LY 302148 is a 5-HT1F receptor agonist with potential for migraine therapeutics.
BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors.
Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.oxapine is a typical antipsych...
Risperidone is a serotonin 5-HT2 receptor blocker and a potent dopamine D2 receptor antagonist.
Almotriptan, also called as Almogran, is a agonist with high and specific affinity for 5-HT1B/1D receptors. developed by Almirall Prodesfarma for the acute trea...
Tianeptine is a selective facilitator of 5-HT uptake in vitro and in vivo with psychostimulant, anti-ulcer and anti-emetic properties.
PRX 08066, a selective 5-hydroxytryptamine receptor 2B(5-HT2BR) antagonist, causes selective vasodilation of pulmonary arteries. Its IC50 value is 3.4 nM. It ca...
SUVN-D4010 is a selective Serotonin 4 receptor partial agonist originated by Suven Life Sciences. Phase I clinical trials for the treatment of Alzheimer's disea...
Mirisetron maleate, an oxoquinoline derivative, has been found to be a 5-HT3 receptor antagonist that could probably be effective against anxiety disorders and ...
Elzasonan, also called as CP 448187, exhibits potent and selective antagonism of 5-HT1B receptors in vitro, and preclinical in vivo studies demonstrate enhanced...
Alprenolol is a non-selective Beta-Adrenergic receptor and 5-HT1A receptor antagonist for the treatment of angina pectoris.
(S)-6-Hydroxybuspirone is a major active metabolite of Buspirone. (R)-Enantiomer showed higher affinity and selectivity for the 5HT1A receptor compared to the ...
Quetiapine D4 fumarate
The isotope labelled form of Quetiapine fumarate, a 5-HT receptor antagonist, is widely used as an antipsychotic drug.